Investigating the biological causes of neurological disorders in veterans
BLR&D Research Career Scientist Award Application
This study is looking into how certain changes in our genes might be linked to brain and nerve disorders, like ALS, that many veterans face, with the hope of finding new and better treatments for those who are struggling with these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | James J Peters VA Medical Center NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project ID | NIH-11063199 on NIH RePORTER |
What this research studies
This research focuses on understanding the molecular mechanisms behind central nervous system disorders that are prevalent among U.S. military veterans, including amyotrophic lateral sclerosis (ALS) and other psychiatric conditions. The Principal Investigator, Dr. Dracheva, employs a multidisciplinary approach that combines genetics, epigenetics, and molecular biology to explore how gene expression is altered in these disorders. By identifying genetic and epigenetic factors, the research aims to uncover new targets for more effective treatments. The ultimate goal is to develop novel medications that can better address the needs of patients suffering from these debilitating conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include veterans diagnosed with amyotrophic lateral sclerosis or other related central nervous system disorders.
Not a fit: Patients who do not have a diagnosis of amyotrophic lateral sclerosis or related CNS disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective treatments for neurological disorders, improving the quality of life for affected patients.
How similar studies have performed: Previous research has shown promise in understanding the biological mechanisms of CNS disorders, indicating that this approach could yield valuable insights.
Where this research is happening
Bronx, United States
- James J Peters VA Medical Center — Bronx, United States (Active)
Researchers
- Principal investigator: Dracheva, Stella — James J Peters VA Medical Center
- Study coordinator: Dracheva, Stella
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.