Sponsor or institution
Clinical trials and research at Harvard Medical School
As of November 12, 2026, Find a Trial lists 497 NIH-funded research projects at this institution, with $290.3 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 497NIH research projects
NIH-funded research (newest 40 of 497)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Comparing End-of-Life Care for Older Adults Across Richer Countries
Aims to understand how end-of-life care for older adults with serious illnesses differs in the US compared with other high-income countries.
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Comparing End-of-Life Care for Older Adults Across Rich Countries
A study compares how end-of-life care is handled for older adults in the US and other high-income countries to identify what might improve care here.
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Comparing End-of-Life Care for Older Adults in Rich Countries
A large study from Harvard Medical School compares how older adults near the end of life are cared for in the US and other top-income countries to understand differences and improve care.
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Comparing End-of-Life Care for Older Adults Across Rich Countries
A study using international data to understand how end-of-life care for older adults with poor prognoses differs across five high‑income countries.
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Comparing End-of-Life Care for Older Adults Across Rich Countries
A research project compares how older adults with serious illnesses receive end-of-life care in the US and other high-income countries to find ways to improve care in the United States.
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Comparing End-of-Life Care for Older Adults Across Rich Countries
A project compares how older adults near the end of life are cared for in the U.S. and other high-income countries to identify ways to improve care and reduce wasteful spending.
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Comparing End-of-Life Care for Older Adults Across High-Income Countries
This project compares how end-of-life care is delivered to older adults with serious illnesses in the US and other wealthy countries to understand where care could be improved in the United States.
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Personalized periodontal care using AI and multimodal data
A study from Harvard Medical School aims to tailor periodontal treatment to each patient by using artificial intelligence and multiple data types to identify distinct disease subtypes.
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Comparing how new cardiovascular treatments are adopted or not adopted in rich countries
A study comparing how different high-income countries decide to approve, use, or stop using advanced heart techniques and how this affects patient outcomes.
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How countries approve and use new cardiovascular treatments compared across rich nations
This project compares how different high-income countries approve and adopt new heart-related treatments and how that affects patient outcomes.
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How high-income countries approve and use advanced heart procedures
This project compares how different rich countries decide to approve, use, and stop using advanced heart procedures and what outcomes patients experience.
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Comparing heart-procedure approvals, adoption, and outcomes across rich countries
This project looks at how new cardiovascular procedures are approved, used, and how well they work in high-income countries to understand why outcomes differ.
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Comparing how cardiovascular procedures are approved and used across rich countries
This grant looks at how different high-income countries decide to approve, use, and stop using newer heart procedures to understand why outcomes and costs differ.
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Comparing heart-procedure approval and use across rich countries
A project will compare how advanced cardiovascular procedures are approved, adopted, or stopped across high-income countries and what that means for patient care.
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Differentiated care to help adolescents with HIV move to adult care in Peru
A community-based program in Lima, Peru tests a tailored support package to help teens living with HIV stay in care and keep their virus under control as they move to adult clinics.
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Digital support to spread team-based schizophrenia care in primary care in India
A project to help frontline health workers in India use digital tools to provide coordinated schizophrenia care in primary care, with plans to inform care in the United States as well.
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Digital support for shared-care of schizophrenia in primary care in India
A patient-friendly plan to bring evidence-based schizophrenia care to primary care in India using digital tools and trained frontline workers.
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Digital support to scale Schizophrenia care in primary care in India
A nationwide effort to help primary care teams in India deliver better, more accessible schizophrenia care using digital tools and trained frontline workers.
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Data Analysis Center for Somatic Mosaicism Across Human Tissues Network
A national network is building a data hub to map mosaic genetic changes across different body tissues to help understand how they influence health and disease.
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Enhancing CFDE Resources with a Universal Discovery Interface
A patient-facing project aims to improve how researchers access and visualize diverse biology data to better understand how gene-regulatory elements influence health.
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Understanding cancer cachexia to improve quality of life and treatment for cancer patients
A Cancer cachexia research project from Harvard Medical School is exploring what causes extreme weight and muscle loss in cancer patients and how to stop it.
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Efficient control of brain signals to improve perceptual decisions
This project tests whether people can reduce neural and behavioral noise during quick, uncertain perceptual decisions by using motivated control of sensory processing.
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Cellular Energy Metabolism in Neurons
Scientists are studying how nerve cells keep up with energy needs on the fly, using new fluorescent sensors to watch energy changes in real neurons.
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Macrophages shaping inflammation and healing in mucosal tissues
This NIH grant explores how macrophages control inflammation and aid tissue repair in mucosal areas, with aim to improve how these tissues recover after damage.
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Understanding lung problems that linger after TB treatment in Peru
A study following people who were treated for TB in Lima, Peru to see what kinds of long-lasting lung problems they have and what factors put them at risk.
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InteroCANCEption: How nerves talk to cancer and the immune system
A cancer-focused project from Harvard Medical School will study how the brain’s internal sensing system talks to tumors and the immune system, with the goal of uncovering new ways to influence cancer growth and fight the disease.
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How chromosomes line up and separate during egg and sperm formation
Researchers are looking at how a zipper-like structure that helps chromosomes pair during egg and sperm formation works, to help reduce miscarriages, infertility, and chromosome birth defects.
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Safer bacteria designed to deliver medicines without spreading their genes
Researchers are designing bacteria that can safely deliver medicines for people with chronic autoimmune conditions by preventing the engineered genes from spreading to other microbes.
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How a gut-linked immune signal (IL-17) may influence Alzheimer's
Researchers are looking at whether an immune protein called IL-17, shaped by gut bacteria and immune cells, can affect Alzheimer's disease in older adults.
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MafB mutations and bone loss in a mouse model of a rare childhood skeletal disease
A study using a mouse model of a very rare childhood bone disorder to understand why MafB mutations cause bone loss and joint pain.
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Understanding how eye cells work together to fight herpes infections
This grant looks at how corneal cells coordinate to stop herpes simplex virus from causing keratitis that can lead to blindness.
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3D imaging and machine learning to map cancer cell and immune cell interactions
A cancer-focused project uses advanced 3D imaging and AI to map how tumor cells and immune cells interact, helping doctors understand tumors better.
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ImmGen Consortium: mapping immune gene activity with AI and advanced sequencing
A collaboration of 25 immunology and computational biology labs is using AI and cutting-edge sequencing to map how immune cells express genes and regulate them across all cell types, making a rich public resource for researchers and clinicians.
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RNA-based test to detect antibiotic resistance in tuberculosis
A new RNA-based test aims to quickly identify drug resistance in Mycobacterium tuberculosis to help tailor treatment.
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Understanding long-term lung problems after TB treatment and who’s at risk in Peru
This study looks at people who were successfully treated for TB in Lima, Peru, to see how common long-lasting lung problems are and who is most at risk.
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How extreme heat and cold affect aging with Alzheimer’s and related dementias
A study exploring how very hot or very cold weather might impact health and daily living for people aged 65 and older who have Alzheimer’s disease or related dementias.
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Medicare, doctors, and patient choices that shape Alzheimer's care quality
The project uses doctors' and patients' judgments together with Medicare data to find what helps people with Alzheimer's get higher-quality care.
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How public long-term care benefits could help people with dementia and their families
This project looks at how different public long-term care benefit designs would affect people with dementia, their families, and who pays for care.
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How Medicare decides prescription drug coverage
This project looks at different ways Medicare covers prescription drugs to find which options help older people afford and get the medicines they need.
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Medicare Advantage: what it means for seniors now and in the future
This project looks at how Medicare Advantage plans affect access to care, costs, and patient experiences for people on Medicare.
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