NIH-funded research NIH-funded research

Enhancing CFDE Resources with a Universal Discovery Interface

Official title: Enhancing CFDE Resources through the Universal Discovery Interface

Funded at Harvard Medical School · NIH-11542184 · Data updated 2026-11-12

A patient-facing project aims to improve how researchers access and visualize diverse biology data to better understand how gene-regulatory elements influence health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionHarvard Medical School
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 19, 2024
Project endAugust 31, 2027
Funding year2026
Award (this year)$508,776
NIH project number3U24OD038421-03S1
Project IDNIH-11542184 on NIH RePORTER

Who could benefit from this research

Could help

Patients whose conditions are related to genetic regulation and gene expression could indirectly benefit from faster translational research and potential new therapies.

Less likely to help

Direct patient participation is not described; the work is primarily data-driven and computational.

What this research studies

This grant supports building a flexible, visualization-first data system that links many large human biology datasets. Researchers will create interactive tools to explore how regulatory DNA regions target genes, using data from GTEx, HuBMAP, SenNet, 4DN, ENCODE and more. The goal is to make it easier for scientists to find meaningful connections between genetic variation, gene regulation, and health outcomes. The work emphasizes FAIR data sharing and customizable visualizations to support future discoveries that could impact human health.

Why it matters

Potential benefit: If successful, the project could speed discoveries in gene regulation that inform disease understanding and treatment development.

How similar studies have gone: Similar integrative visualization efforts have shown promise in enabling researchers to interpret complex genomic data.

Where this research is happening

  • Harvard Medical School
    Boston, United States
    Active

Researchers

  • Principal investigator: Gehlenborg, Nils — Harvard Medical School
  • Study coordinator: Gehlenborg, Nils

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.