NIH-funded research R01 grant

Comparing heart-procedure approvals, adoption, and outcomes across rich countries

Official title: Comparing approval, adoption/de-adoption and outcomes for advanced cardiovascular procedures across high-income countries

Funded at Harvard Medical School · NIH-11596352 · Data updated 2026-11-12

This project looks at how new cardiovascular procedures are approved, used, and how well they work in high-income countries to understand why outcomes differ.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHarvard Medical School
NIH-funded
Lab location1 site (Boston, United States)
Project startFebruary 21, 2024
Project endJanuary 31, 2028
Funding year2026
Award (this year)$25,920
NIH project number3R01HL167887-03S3
Project IDNIH-11596352 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adults with cardiovascular conditions treated by advanced procedures in high-income countries participating in the study.

Less likely to help

Patients in systems not yet applying HTA or sharing data may see indirect benefits through broader policy insights.

What this research studies

Researchers at Harvard Medical School will use an existing international research network to compare how different countries evaluate and adopt advanced cardiovascular procedures and how these choices affect patient outcomes. They will analyze health technology assessment processes and link them to real-world use of treatments and to patient results across multiple countries. The work builds on prior international collaboration to study heart disease care and aims to reveal factors behind spending and outcomes differences. The study will use observational data from diverse health systems to identify patterns and potential improvements in decision making for cardiovascular care.

Why it matters

Potential benefit: If successful, this work could inform policy and clinical practice to optimize cardiovascular care and reduce unnecessary spending.

How similar studies have gone: Previous international collaborations have shown that HTA and policy decisions influence treatment adoption and outcomes, supporting this line of research.

Where this research is happening

  • Harvard Medical School
    Boston, United States
    Active

Researchers

  • Principal investigator: Landon, Bruce E. — Harvard Medical School
  • Study coordinator: Landon, Bruce E.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.