How countries approve and use new cardiovascular treatments compared across rich nations
Official title: Comparing approval, adoption/de-adoption and outcomes for advanced cardiovascular procedures across high-income countries
Funded at Harvard Medical School · NIH-11596355 · Data updated 2026-11-12
This project compares how different high-income countries approve and adopt new heart-related treatments and how that affects patient outcomes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Medical School NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | February 21, 2024 |
| Project end | January 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $14,904 |
| NIH project number | 3R01HL167887-03S6 |
| Project ID | NIH-11596355 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with cardiovascular conditions in high-income countries where treatments or procedures have recently been adopted or debated, and who are impacted by access or coverage decisions.
✕Less likely to help
Patients in systems with rapid, consistent adoption and optimal outcomes may see limited direct benefit if their settings already reflect best-value decisions.
What this research studies
If you or a loved one has a cardiovascular condition, this work looks at how health systems decide which new heart procedures and therapies to use. Researchers will link international data to see how official recommendations and coverage decisions influence real-world use, adoption, and de-adoption of treatments after they arrive. The goal is to understand why spending is high in the US yet outcomes lag behind peers, and what policy choices might improve value and life expectancy. The project builds on existing international collaboration to examine health technology assessment and its impact on patient care across countries.
Why it matters
Potential benefit: If successful, this work could inform policies that align treatment adoption with value, potentially improving outcomes and reducing unnecessary spending for patients.
How similar studies have gone: Previous international collaborations have shown that HTA and funding decisions influence treatment use, but this project expands direct cross-country comparisons for cardiovascular care.
Where this research is happening
-
Harvard Medical School
Boston, United States Active
Researchers
- Principal investigator: Landon, Bruce E. — Harvard Medical School
- Study coordinator: Landon, Bruce E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.