NIH-funded research R01 grant

Differentiated care to help adolescents with HIV move to adult care in Peru

Official title: Efficacy of a differentiated care intervention for adolescents transitioning to adult HIV care in Peru

Funded at Harvard Medical School · NIH-11580917 · Data updated 2026-11-12

A community-based program in Lima, Peru tests a tailored support package to help teens living with HIV stay in care and keep their virus under control as they move to adult clinics.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHarvard Medical School
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 15, 2022
Project endJune 30, 2027
Funding year2026
Award (this year)$207,616
NIH project number3R01MH131414-05S1
Project IDNIH-11580917 on NIH RePORTER

Who could benefit from this research

Could help

Adolescents and young adults living with HIV in Lima, Peru, who are transitioning from pediatric to adult care.

Less likely to help

The intervention may be less beneficial for individuals without barriers to care or without identified adherence or transition readiness needs.

What this research studies

This project builds on an established community health platform to support adolescents and young adults with HIV in Peru during the transition to adult care. It uses a two-arm randomized trial to test how well the differentiated care approach works for retention in care and viral suppression, along with measures of well-being. The intervention includes help with housing stability, navigation of health systems, accompaniment to appointments, peer groups, skills-building, and mental health screening and referral, with intensity adjusted to each participant’s needs. Outcomes will cover short- and long-term effectiveness, costs, and implementation factors to guide future use. The study leverages prior pilot data showing acceptability and improvements in adherence and readiness for transition.

Why it matters

Potential benefit: If successful, the program could improve HIV care continuity and health outcomes for adolescents transitioning to adult services.

How similar studies have gone: Preliminary pilot data indicated high acceptability and positive changes in adherence and readiness.

Where this research is happening

  • Harvard Medical School
    Boston, United States
    Active

Researchers

  • Principal investigator: Franke, Molly Forrest — Harvard Medical School
  • Study coordinator: Franke, Molly Forrest

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.