How high-income countries approve and use advanced heart procedures
Official title: Comparing approval, adoption/de-adoption and outcomes for advanced cardiovascular procedures across high-income countries
Funded at Harvard Medical School · NIH-11596354 · Data updated 2026-11-12
This project compares how different rich countries decide to approve, use, and stop using advanced heart procedures and what outcomes patients experience.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Medical School NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | February 21, 2024 |
| Project end | January 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $15,711 |
| NIH project number | 3R01HL167887-03S5 |
| Project ID | NIH-11596354 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with cardiovascular conditions who may be affected by changes in treatment availability or coverage decisions in their country.
✕Less likely to help
Patients in regions with already optimal HTA-informed adoption patterns or those not impacted by cross-country policy differences may see limited direct benefit.
What this research studies
Researchers will build on an existing international research network to compare how health technology assessments influence which cardiovascular treatments are adopted or de-adopted in countries like the US, Canada, the UK, the Netherlands, and Australia. The study will analyze how coverage decisions relate to the actual use of procedures and the health outcomes of patients with conditions such as aneurysms and heart valve disease. By examining large datasets across countries, it aims to identify why the US spends more on care but has relatively poorer cardiovascular outcomes, with the goal of informing better policy and practice. The findings could help patients receive effective, evidence-based treatments sooner and avoid unnecessary or outdated technologies.
Why it matters
Potential benefit: Could help align healthcare spending with proven benefits, improving cardiovascular care for patients.
How similar studies have gone: Prior work has shown that HTA processes influence adoption of new therapies in several countries, but this project expands to international comparisons and patient outcomes.
Where this research is happening
-
Harvard Medical School
Boston, United States Active
Researchers
- Principal investigator: Landon, Bruce E. — Harvard Medical School
- Study coordinator: Landon, Bruce E.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.