NIH-funded research R01 grant

Comparing heart-procedure approval and use across rich countries

Official title: Comparing approval, adoption/de-adoption and outcomes for advanced cardiovascular procedures across high-income countries

Funded at Harvard Medical School · NIH-11596349 · Data updated 2026-11-12

A project will compare how advanced cardiovascular procedures are approved, adopted, or stopped across high-income countries and what that means for patient care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHarvard Medical School
NIH-funded
Lab location1 site (Boston, United States)
Project startFebruary 21, 2024
Project endJanuary 31, 2028
Funding year2026
Award (this year)$32,326
NIH project number3R01HL167887-03S1
Project IDNIH-11596349 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adults with cardiovascular conditions who could benefit from modern procedures and live in high-income countries participating in the study.

Less likely to help

Patients in countries not included in the comparison or those undergoing procedures not yet subject to HTA analysis may see limited direct impact.

What this research studies

From a patient perspective, this work looks at how different countries decide which cardiovascular treatments get funded and used, and how these decisions affect real-world outcomes. The researchers will use international data to map approval timelines, adoption rates, and when procedures fall out of favor, linking those patterns to patient results. The goal is to understand how policy and health technology assessments shape access to cutting-edge therapies for heart disease. This could help explain why some patients in the US experience higher costs with variable outcomes, and identify opportunities to improve care delivery. The project builds on established IHSRC infrastructure to compare countries and examine how decisions impact treatment choices.

Why it matters

Potential benefit: If successful, the study could highlight policies that improve access to effective cardiovascular therapies while reducing unnecessary spending.

How similar studies have gone: Prior international comparisons have shown meaningful differences in adoption and outcomes, suggesting that policy and HTA processes influence care.

Where this research is happening

  • Harvard Medical School
    Boston, United States
    Active

Researchers

  • Principal investigator: Landon, Bruce E. — Harvard Medical School
  • Study coordinator: Landon, Bruce E.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.