NIH-funded research NIH-funded research

Personalized periodontal care using AI and multimodal data

Official title: Advancing Personalized Periodontal Therapy Using AI and Multimodal Data Integration

Funded at Harvard Medical School · NIH-11607778 · Data updated 2026-11-12

A study from Harvard Medical School aims to tailor periodontal treatment to each patient by using artificial intelligence and multiple data types to identify distinct disease subtypes.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionHarvard Medical School
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 18, 2026
Project endSeptember 17, 2028
Funding year2026
Award (this year)$1,352,161
NIH project number1R56DE035177-01A1
Project IDNIH-11607778 on NIH RePORTER

Who could benefit from this research

Could help

Individuals with periodontitis or at-risk patients who consent to participate and share clinical, microbiological, and immunological data.

Less likely to help

Patients without periodontitis or those unwilling to share data or undergo proposed assessments may not benefit.

What this research studies

This project seeks to move beyond one-size-fits-all gum disease care by combining clinical data, microbiology, and immune system information with AI to find patient-specific periodontal profiles. Researchers will use multimodal data and machine learning to define phenotypes and predict how different treatment plans will work for each phenotype. The goal is to develop precision treatment strategies that improve outcomes and reduce unnecessary or ineffective therapies for people with periodontitis. If successful, the approach could enable dentists to customize cleaning, medications, and surgical choices based on an individual’s biology and clinical presentation.

Why it matters

Potential benefit: Patients could receive more effective, personalized periodontal care leading to better tooth preservation and overall health.

How similar studies have gone: AI-driven precision dentistry is being explored, with early signals suggesting improved customization of treatments.

Where this research is happening

  • Harvard Medical School
    Boston, United States
    Active

Researchers

  • Principal investigator: Feres, Magda — Harvard Medical School
  • Study coordinator: Feres, Magda

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.