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Clinical trials and research at Dartmouth-Hitchcock Medical Center

• 59Clinical trials
• 2Countries

Newest trials

All recruiting trials (59)

• HOBSCOTCH for Young Adults with Epilepsy

  This study tests a nine-week home-based program to help young adults (18-29) with epilepsy improve thinking, memory, and quality of life, and also tests a version adapted for youths (13-17) with a parent to see if it helps their thinking, memory, and stress levels for families.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT07735715

• Remotely Delivered Physical Activity Pathways for Breast Cancer Survivors

  This study tests whether breast cancer survivors who are less active at 6 weeks can be randomized to continue the standard activity program or move to a more intensive step-up program to see if retention and engagement improve.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT07706556

• Telehealth CBT for insomnia tailored to ulcerative colitis

  This pilot will test whether telehealth cognitive behavioral therapy for insomnia, adapted for adults with ulcerative colitis, can improve sleep and is acceptable to patients.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT07428629

• Trauma‑Focused Cognitive Behavioral Therapy adapted for autistic children and teens (pilot implementation)

  This pilot will try TF‑CBT adapted for autistic children and teens with trauma-related symptoms to see if community mental health clinicians can deliver it and families find it acceptable.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT07420478

• Nerve-labeling dye to help protect major nerves during surgery

  This study tests LGW16-03, a dye given by IV before open-field orthopedic surgery to see if it is safe and if it improves nerve visualization for patients undergoing procedures with a major nerve.

  Recruiting Phase 1 Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT07385430

• Hyperbaric oxygen for chronic radiation cystitis

  This project will try hyperbaric oxygen therapy in adults with moderate to severe radiation cystitis to see if symptoms improve and urine inflammatory markers change.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT07368647

• Plan & Protect safety planning for teens in rural EDs

  A tablet-based safety planning program is being tested in rural emergency departments to see if it helps families make homes safer and lowers suicide risk for 12-17 year olds.

  Recruiting at 5 sites Dartmouth-Hitchcock Medical Center · Claremont, New Hampshire and 5 other locations · NCT07325474

• Gut response to a Mediterranean diet in children with cystic fibrosis

  This project will try a Mediterranean-style diet in children with cystic fibrosis to see if it lowers gut inflammation, shifts the gut microbiome toward healthier bacteria, and supports better nutrition.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire and 1 other locations · NCT07223255

• Chronic Kidney Disease: Testing a Structured Agenda-Setting Tool for Advanced CKD Patients

  We’re testing a simple, structured discussion tool called CKD Topics with adults with advanced CKD (stages 4–5) to see how well it works before a larger study.

  Recruiting Dartmouth-Hitchcock Medical Center · Keene, New Hampshire and 1 other locations · NCT07221604

• PpIX fluorescence tissue oxygen imaging to tell benign from non-melanoma skin lesions

  This project will test a PpIX-based tissue oxygen imager to see if it can tell benign skin growths from non-melanoma skin cancers in adults who have lesions scheduled for removal.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT07201376

• Electronic symptom reporting to connect people with advanced cancer to palliative care

  This project tests whether weekly electronic symptom surveys plus monthly needs questionnaires can help adults with advanced metastatic solid tumors get connected to palliative and supportive care sooner.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT07195513

• Remote Depression Monitoring with Smartphone Data and Alerts

  This study tests whether data from a patient's smartphone can help predict if depressive symptoms will come back after treatment.

  Recruiting at 2 sites Dartmouth-Hitchcock Medical Center · Hanover, New Hampshire and 1 other locations · NCT07174557

• I-CARE digital program to teach coping skills during psychiatric boarding

  This project will test whether the I-CARE digital program helps adolescents (ages 12–17) boarding in the emergency department for suicide risk learn coping skills and feel less distressed.

  Recruiting at 2 sites Dartmouth-Hitchcock Medical Center · New Haven, Connecticut and 3 other locations · NCT07150832

• Post-surgery nutrition shake to help recovery in older adults

  We will try a daily nutritional shake after surgery to see if it helps people 70 and older recover their strength and thinking compared with standard postoperative nutrition instructions.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT07109505

• Switching aromatase inhibitors versus guideline-based side-effect care to help with AI side effects

  This test tries switching one aromatase inhibitor to another versus using guideline-based side-effect care to see which helps postmenopausal women with early-stage ER-positive breast cancer stay on their hormone therapy.

  Recruiting Phase 2 Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT07071038

• ABY-029 to highlight gliomas during surgery

  This will test whether tiny doses of ABY-029 help surgeons see glioma tumors better during open brain surgery in adults.

  Recruiting Phase 1 Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT07063693

• Alternating gemcitabine + nab-paclitaxel and modified FOLFIRINOX for borderline resectable pancreatic cancer

  This trial will try alternating two chemotherapy regimens, gemcitabine with nab-paclitaxel and modified FOLFIRINOX, before surgery for people with borderline resectable pancreatic adenocarcinoma.

  Recruiting Phase 2 Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT07043270

• Trauma, PTSD, and resilience in adults living with congenital heart disease

  This project will test whether lifetime experiences related to congenital heart disease are linked to PTSD and whether resilience helps protect adults with CHD.

  Recruiting Dartmouth-Hitchcock Medical Center · Washington D.C., District of Columbia and 2 other locations · NCT06952933

• HOBSCOTCH-MS: Home-based telehealth cognitive coaching for people with multiple sclerosis

  This program will test whether a home-based telehealth cognitive coaching program (HOBSCOTCH-MS) can improve thinking, memory, and quality of life for people with MS and reduce caregiver burden.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06951919

• Home-based self-management and cognitive training for brain tumor survivors

  This trial will try a home-based cognitive coaching program to see if it improves thinking and quality of life for adults who survived non-glioblastoma brain tumors, with optional caregiver participation.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06930846

• Improving patient engagement in collaborative care for anxiety and depression

  This study is testing a new way to involve patients more in their anxiety and depression treatment by using their personal goals to see if it makes them and their doctors happier with the care they receive.

  Recruiting at 6 sites Dartmouth-Hitchcock Medical Center · Concord, New Hampshire and 5 other locations · NCT06898593

• Real-time detection of necrotizing soft tissue infection using indocyanine green imaging

  We will test whether injecting indocyanine green and tracking its fluorescence over time can quickly and accurately detect necrotizing soft tissue infections in adults suspected of having NSTI.

  Recruiting at 8 sites Dartmouth-Hitchcock Medical Center · Los Angeles, California and 7 other locations · NCT06877793

• Electrical bioimpedance imaging for high-energy limb fractures

  This will test whether a portable electrical impedance tomography (EIT) device can image tissue changes in adults with high-energy closed limb fractures.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06858488

• Comparing consultative versus collaborative ways patients, clinicians, and the public partner with health teams.

  This project will test whether a consultative or a collaborative way of involving patients, care partners, clinicians, and community members leads to better engagement and trust when they work with research teams on qualitative projects about pediatric mental health, cancer screening, and serious illness.

  Recruiting at 2 sites Dartmouth-Hitchcock Medical Center · Hanover, New Hampshire and 1 other locations · NCT06838689

• Telmisartan with standard chemotherapy for platinum-resistant ovarian cancer

  This test will see if adding telmisartan to standard chemotherapy helps people with platinum-resistant high-grade serous ovarian cancer live longer without their disease getting worse.

  Recruiting at 2 sites Phase 2 Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire and 1 other locations · NCT06815497

• ICG fluorescence imaging to show bone blood flow in open fractures and infections

  This will test whether a dye-based fluorescence camera can show bone blood flow in adults with open fractures or bone infections so surgeons can choose the best treatment.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06793644

• Reducing harm for smokers with mental illness using e-cigarettes

  This study is testing whether giving e-cigarettes with or without online support can help daily smokers with serious mental illness manage stress and reduce harm, even if they aren't ready to quit smoking yet.

  Recruiting at 2 sites Dartmouth-Hitchcock Medical Center · Louisville, Kentucky and 1 other locations · NCT06543407

• Mammogram decision support for women in rural areas

  This pilot will try a patient decision aid, with or without a clinician communication intervention, to help women aged 40–49 in rural primary care decide about mammography.

  Recruiting at 3 sites Dartmouth-Hitchcock Medical Center · Keene, New Hampshire and 2 other locations · NCT06522568

• Evaluating a new aortic endograft for treating thoracoabdominal aneurysms

  This study is testing a new type of aortic stent to see if it’s a safer and more effective option for high-risk patients with thoracoabdominal aneurysms compared to traditional surgery.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06501872

• One-of-a-kind self‑administered web music therapy for epilepsy

  This test sees if daily listening to specific music through a web app can reduce epileptic brain activity in adults with medication‑resistant focal epilepsy who have an RNS implant.

  Recruiting Dartmouth-Hitchcock Medical Center · Worcester, Massachusetts and 1 other locations · NCT06425029

• Hydroxychloroquine before prostate removal for resectable localized prostate cancer

  This randomized, double-blind study tests whether taking hydroxychloroquine before prostatectomy changes tumor autophagy markers and drug levels in men with resectable localized prostate cancer.

  Recruiting Early Phase 1 Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06408298

• Evaluating a new imaging system for breast cancer management

  This study is testing a new imaging system to see if it can help women recently diagnosed with breast cancer get better information for their treatment planning compared to standard MRI.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06400563

• RetracTOR 3D-printed polymer retractor for trans-oral surgery

  This study will test whether a 3D-printed polymer mouth retractor holds the mouth open as well as a standard metal retractor during endoscopy and throat surgery for adults with suspected lesions of the oral cavity, oropharynx, hypopharynx, or larynx.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06381505

• Using radiation therapy to prevent Dupuytren's contracture recurrence after treatment

  This study is testing if targeted radiation therapy can help prevent Dupuytren's contracture from coming back after treatment in people aged 45 and older.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06330545

• Testing a new way to promote exercise for breast cancer survivors

  This study is testing a new exercise program for breast cancer survivors to see if focusing on how they feel while exercising helps them be more active than a traditional program.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06258993

• Immediate biopsy versus active ultrasound monitoring for suspicious thyroid nodules

  This will try immediate biopsy versus careful ultrasound monitoring to see which causes less anxiety and better thyroid-related quality of life for adults with newly found suspicious thyroid nodules (TI‑RADS 4–5) that are 2 cm or smaller.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06220656

• Testing telmisartan for tolerability in prostate cancer patients

  This study is testing if the medication telmisartan is safe and well-tolerated for men with prostate cancer when taken alone or with their usual treatments.

  Recruiting Phase 1 Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06168487

• Combining Tetrathiomolybdate with Capecitabine for Triple Negative Breast Cancer

  This study is testing if adding a new drug called tetrathiomolybdate to the usual treatment for high-risk triple negative breast cancer can help patients who still have cancer after their initial therapy.

  Recruiting at 2 sites Phase 1/2 Dartmouth-Hitchcock Medical Center · Indianapolis, Indiana and 2 other locations · NCT06134375

• Modulating pulse-width during spinal surgery

  This study is testing how different settings of electrical stimulation during spinal surgery can affect the safety and effectiveness of the procedure for patients.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06120231

• Assessing immune profiles to predict responses to cancer immunotherapy

  This study is testing if certain immune profiles can help predict how well cancer patients will respond to approved immunotherapy treatments.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06116032

• Understanding how people with Mild Cognitive Impairment hear and process sounds

  This study is testing how well people with Mild Cognitive Impairment hear and understand sounds compared to healthy individuals.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06102486

• Device for detecting leftover prostate cancer tissue during surgery

  This study is testing a special device to see if it can help doctors find leftover prostate cancer tissue during surgery to improve outcomes for men with prostate cancer.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06039085

• Evaluating C7 Nerve Transfer for Stroke Recovery

  This study is testing if a surgery that connects a healthy part of the brain to the arm can help people who haven't improved their arm function after a stroke for 1-5 years.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06001736

• Effects of Modulator Therapy on Cystic Fibrosis Microbiome

  This study is trying to see how a new treatment for cystic fibrosis affects the bacteria in the sinuses and overall health of adults with the condition.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT05982795

• Improving chronic illness care experience for older adults through visit notes and audio recordings

  This study tests if giving older adults access to their healthcare visit notes and audio recordings can help them better manage chronic conditions like diabetes and hypertension.

  Recruiting at 2 sites Dartmouth-Hitchcock Medical Center · Manchester, New Hampshire and 2 other locations · NCT05955339

• Genetically-informed therapy for advanced ER+ breast cancer after CDK4/6 inhibitors

  This study is testing different drug combinations to see if they can help post-menopausal women with advanced ER+/HER2- breast cancer who have already been treated with certain medications.

  Recruiting Phase 2 Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT05933395

• Combination of estradiol and olaparib for advanced breast cancer treatment

  This study is testing a new treatment combining estradiol and olaparib to see if it helps post-menopausal women with advanced breast cancer that hasn't responded to other therapies.

  Recruiting Phase 1 Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT05900895

• Testing home air for radon to improve lung cancer prevention

  This study is trying to see if different ways of encouraging people, especially smokers and non-smokers, to test their homes for radon can help prevent lung cancer.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT05833334

• Using light-based imaging for open and infected fractures

  This study is testing a new light-based imaging method to see if it can help doctors better diagnose and manage open or infected fractures without using drugs or contrast agents.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT05785182

• Individualized chemotherapy dosing for gastrointestinal cancer

  This study tests whether giving personalized doses of chemotherapy can help people with advanced gastrointestinal cancers do better with their treatment.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT05780684

• Estradiol treatment for advanced breast cancer with specific mutations

  This study is testing if a hormone treatment called estradiol can help post-menopausal women with advanced breast cancer that has specific mutations feel better and live longer compared to those without those mutations.

  Recruiting Phase 2 Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT05716516

• Comparing colonoscopy and stool testing for older adults with colon polyps

  This study is testing whether a simple stool test can be just as effective as colonoscopy for monitoring older adults with a history of colon polyps.

  Recruiting at 22 sites Dartmouth-Hitchcock Medical Center · Birmingham, Alabama and 23 other locations · NCT05612347

• Investigating brain function in epilepsy patients using implanted electrodes

  This study is testing how well different parts of the brain work in people with epilepsy who are getting ready for surgery, by using implanted electrodes to record brain activity while they do memory and attention tasks.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT05529264

• Cancer treatment guided by a Molecular Tumor Board at Dartmouth

  This study is testing if treatment suggestions from a special group of experts can help doctors make better choices for cancer patients at Dartmouth Cancer Center.

  Recruiting Phase 2 Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT05405413

• Evaluating the CONVIVO System for Brain Tumor Surgery

  This study is testing a new imaging tool during brain tumor surgery to see if it can better tell the difference between healthy and unhealthy brain tissue for patients with brain tumors.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT05139277

• Measuring brain responses to visual stimuli in people with hearing loss

  This study is testing how the brain responds to visual images in people with hearing loss to see if it can help improve treatments for their condition.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT05107466

• Using Low-Dose Naltrexone to Treat Painful Diabetic Neuropathy

  This study is testing if low-dose naltrexone can help people with painful diabetic neuropathy feel less pain after other treatments haven't worked.

  Recruiting Phase 2 Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT04678895

• Improving thumb strength and function for arthritis patients

  This study is testing different surgical options for people with thumb arthritis to see which one helps improve strength, function, and reduce pain the most.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT04458584

• Internet-based psychological support for depression and stress management

  This study is testing an online program that helps people manage depression and stress through interactive lessons and support to see if it works well for them.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT02726061

Quick answers

How many clinical trials run by Dartmouth-Hitchcock Medical Center are recruiting right now?

59, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (59 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 7, Phase 1: 4, Phase 1/2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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