Clinical trial Recruiting at 1 site Interventional Ages 13 to 29

HOBSCOTCH for Young Adults with Epilepsy

Official title: HOBSCOTCH-YOUTH and Young Adults

Run by Dartmouth-Hitchcock Medical Center · NCT07735715 · Data updated 2026-11-12

This study tests a nine-week home-based program to help young adults (18-29) with epilepsy improve thinking, memory, and quality of life, and also tests a version adapted for youths (13-17) with a parent to see if it helps their thinking, memory, and stress levels for families.

Quick facts

Study typeInterventional
Ages13 Years to 29 Years
SexAll
Enrollment300 (estimated)
SponsorDartmouth-Hitchcock Medical Center
Academic / other
Locations1 site (Lebanon, New Hampshire)
StatusRecruiting
StartedSeptember 1, 2026
Main results expectedMay 1, 2029
Study endsJuly 31, 2029
Registry record updatedNovember 2, 2026
Trial IDNCT07735715 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Young adults aged 18-29 with epilepsy, and youths aged 13-17 with epilepsy (with a participating parent/guardian for the youth), who have subjective cognitive concerns and access to internet and a device.

Probably not a fit

Participants without cognitive concerns or those unable to engage in home-based, internet-enabled sessions may see little or no benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial will enroll about 260 young adults with epilepsy and 40 youths with epilepsy along with a parent or guardian. Participants will complete questionnaires before and after the program to measure changes in cognitive function and quality of life. The intervention consists of nine weekly one-hour, home-based sessions led by a coach via computer or phone. A modified version of the program for youth is being evaluated for cognitive benefits and family stress. The study is conducted at a single site under Dartmouth-Hitchcock Medical Center.

Why it matters

Potential benefit: If successful, participants may experience improved memory, attention, and overall quality of life related to epilepsy.

How similar studies have gone: Prior home-based self-management programs for epilepsy have shown signals of cognitive and quality-of-life improvements, but this specific youth-adapted approach is novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Inclusion Criteria for Young Adults with Epilepsy (YAWE) and Youth with Epilepsy (YWE):

  * Age 18 - 29 years for YAWE
  * Age 13 - 17 years for YWE
  * For YWE at least one parent or legal guardian provides consent and agrees to participate
  * Diagnosis of epilepsy (controlled or uncontrolled seizures)
  * Subjective cognitive complaints (memory, attention, learning, problem solving, executive function, planning)
  * Literate and proficient in English
  * Telephone access
  * Internet Access.

Inclusion Criteria for Parent of Youth with Epilepsy (YWE):

* Parent or legal guardian of a youth with epilepsy (age 13 - 17 years)
* Literate and proficient in English
* Telephone access
* Internet Access

Exclusion Criteria:

* Active psychosis (any participant)
* Illicit substance abuse (any participant)
* Severe cognitive/intellectual disability (any participant)
* YWE cannot participate without a parent and parent's consent (or legal guardian)
* YWE cannot participate without assent even if a parent or legal guardian gives consent

Where it's running

  • Dartmouth-Hitchcock
    Lebanon, New Hampshire, United States
    Recruiting

Study contacts

  • Principal investigator: Elaine T. Kiriakopoulos, MD, MPH, MSc — Dartmouth-Hitchcock/Geisel School of Medicine-Dartmouth
  • Study coordinator: Wren M Kaden, BA
  • Email: wren.m.kaden@hitchcock.org
  • Phone: 603-650-4225

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.