Improving thumb strength and function for arthritis patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of different surgical interventions for thumb basal joint arthritis, focusing on trapeziectomy with ligament reconstruction, suture suspensionplasty, and arthroscopic trapeziectomy. It aims to determine which approach leads to better functional outcomes, strength, and pain relief. Participants will undergo one of the specified procedures and will be assessed through various clinical measures before and after surgery. The study will collect data on grip and pinch strength, as well as patient-reported outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Males and females 21 years of age or older;
* Undergoing elective non-prosthetic, primary basal joint arthroplasty;
* Patient has necessary mental capacity to participate and comply with study protocol;
* Patient is willing and able to give informed consent; and
* Patient is willing to participate under the care of their chosen surgeon.

Exclusion Criteria:

* Patients with a diagnosis of rheumatoid arthritis, systemic lupus erythematosis, psoriatic arthritis, or other related inflammatory arthritis;
* Patients undergoing simultaneous bilateral hand procedures of any nature;
* Women who are pregnant or breastfeeding;
* Women of reproductive potential unless there is a negative urine pregnancy test on the day of surgery. Women of child bearing potential include those who are premenopausal who have not had a bilateral oophorectomy, hysterectomy or tubal ligation. Post-menopausal is defined as not having had a menstrual period for at least one calendar year.
* Vulnerable patient populations including prisoners and institutionalized individuals.

Where it's running

• Dartmouth-Hitchcock Medical Center
  Lebanon, New Hampshire, United States Recruiting

Study contacts

• Principal investigator: Vincent D Pellegrini, MD — Dartmouth-Hitchcock Medical Center
• Study coordinator: Vincent D Pellegrini, MD
• Email: Vincent.D.Pellegrini.Jr@hitchcock.org
• Phone: (603) 650-5133

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.