Remote Depression Monitoring with Smartphone Data and Alerts
Official title: Beyond the Clinic: Enhancing Depression Surveillance With a Digital Biomarker
Run by Dartmouth-Hitchcock Medical Center · NCT07174557 · Data updated 2026-11-12
This study tests whether data from a patient's smartphone can help predict if depressive symptoms will come back after treatment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 320 (estimated) |
| Sponsor | Dartmouth-Hitchcock Medical Center Academic / other |
| Locations | 2 sites (Hanover, New Hampshire and 1 other locations) |
| Status | Recruiting |
| Started | May 20, 2026 |
| Main results expected | April 1, 2028 |
| Study ends | June 30, 2028 |
| Registry record updated | August 11, 2026 |
| Trial ID | NCT07174557 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) treated for depression in Dartmouth collaborative care settings who have a smartphone and can use it.
✕Probably not a fit
People without smartphone access, incompatible devices, or with ongoing high suicide risk may see limited or no benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers will collect smartphone sensor data and monthly mood questionnaires from adults treated for depression to see if patterns in the data can predict relapse. The study has two phases: an initial six-month observational phase, followed by a randomized phase comparing usual care to using a MoodTriggers app that collects sensor data. Group A uses the app; Group B receives usual care, and both groups complete monthly mood surveys. The goal is to develop a tool that helps providers monitor patients and intervene earlier if symptoms return.
Why it matters
Potential benefit: If successful, clinicians may have a real-time tool to detect relapse risk and intervene sooner to prevent worsening symptoms.
How similar studies have gone: Previous work in digital phenotyping has shown promise in predicting mood changes, but this exact approach in a randomized, care-integrated setting is being explored.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients (18 years or older) * Treated for depression within Dartmouth Health collaborative care model (CoCM) sites who are discharged from CoCM without depression (PHQ-9 \< 10) * Have access to and ability to use a smartphone (Android version ≥ 6 or iOS version ≥ 11). Exclusion Criteria: * Identified as high risk due to active suicidality, psychosis, or bipolar disorder - Discharged from CoCM with ongoing depressive symptoms (PhQ-9 \> 10
Where it's running
-
Dartmouth College
Hanover, New Hampshire, United States Recruiting -
Dartmouth-Hitchcock Clinics
Lebanon, New Hampshire, United States Recruiting
Study contacts
- Principal investigator: Nicholas C Jacobson, PhD — Dartmouth College
- Study coordinator: Nicholas C Jacobson, PhD
- Email: nicholas.c.jacobson@dartmouth.edu
- Phone: (603) 646-7037
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.