Using light-based imaging for open and infected fractures
Optical Coherence Tomography Imaging to Visualize Bacteria or Biofilm on Hardware, Bone and Soft Tissue in Open Fracture and Infected Fracture
This study is testing a new light-based imaging method to see if it can help doctors better diagnose and manage open or infected fractures without using drugs or contrast agents.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Dartmouth-Hitchcock Medical Center Academic / other |
| Locations | 1 site (Lebanon, New Hampshire) |
| Trial ID | NCT05785182 on ClinicalTrials.gov |
What this trial studies
This pilot observational study evaluates the feasibility and acceptability of optical coherence tomography (OCT) in patients with open or infected fractures. The study aims to assess how well this light-based imaging technique can be integrated into clinical practice without the need for drugs or contrast agents. By observing patients with these specific fracture types, researchers will gather data on the effectiveness of OCT in diagnosing and managing these injuries.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 years or older who have an open fracture or a fracture-related infection.
Not a fit: Patients with metatarsal fractures will not benefit from this study as they are excluded from participation.
Why it matters
Potential benefit: If successful, this study could improve the diagnostic capabilities for patients with open or infected fractures, leading to better treatment outcomes.
How similar studies have performed: While this approach is relatively novel, similar imaging techniques have shown promise in other contexts, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 years or older * Open fracture * Fracture Related Infection Exclusion Criteria: * Metatarsal fractures
Where this trial is running
Lebanon, New Hampshire
- Dartmouth-Hitchcock Medical Center — Lebanon, New Hampshire, United States (Recruiting)
Study contacts
- Principal investigator: Ida L Gitajn — Dartmouth-Hitchcock Medical Center
- Study coordinator: Holly B Symonds
- Email: Holly.B.Symonds@hitchcock.org
- Phone: 603-653-9440
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.