Sponsor or institution
Clinical trials and research at Charles University, Czech Republic
As of November 12, 2026, Find a Trial lists 27 clinical trials run by Charles University, Czech Republic that are recruiting, at sites in 2 countries (most in Czechia (27), Slovakia (1)). 1 was first registered in the last 30 days. By phase: Phase 3 (2), Phase 4 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 27Clinical trials
- 1New in 30 days
- 2Countries
Newest trials
All recruiting trials (27)
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4D Transperineal Ultrasound to Check UVJ Mobility After Vaginal Laser for Stress Incontinence
This study tests whether three sessions of self-paid vaginal Er:YAG laser treatment change urethrovesical junction mobility in women with stress urinary incontinence.
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Endometriosis affecting the urinary tract: long-term outcomes and kidney function
This study looks at how deep endometriosis that touches the urinary tract affects the kidneys over time in adults with hydronephrosis or ureteral blockage.
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Mild Sedation with Remimazolam and Fentanyl During Pulsed-Field Ablation for Atrial Fibrillation
This study tests whether a light, monitored sedation with remimazolam and fentanyl during REM (pulsed-field) ablation for AF can replace deeper anesthesia in adults.
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Conservative vs Interventional Management of Postsurgical CSF Pseudomeningocele
This study tests whether non-surgical care or a surgical/drainage approach works better for a CSF pseudomeningocele after brain surgery in eligible patients.
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Left atrial and appendage function after pulsed-field pulmonary vein isolation in paroxysmal AF
We will test whether pulsed-field pulmonary vein isolation causes immediate changes in left atrial and left atrial appendage function in adults with paroxysmal atrial fibrillation.
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Extended ablation added to PVI for persistent atrial fibrillation
In adults with symptomatic persistent AF who are undergoing a first ablation, the study tests whether adding predefined linear ablation lines to pulmonary vein isolation improves freedom from AF/AT/AFL over 12 months.
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Electroconvulsive therapy combined with transcranial magnetic stimulation for treatment-resistant depression
This will test whether giving a short burst of intermittent theta-burst magnetic stimulation (iTBS) just before electroconvulsive therapy helps adults with treatment-resistant major depressive disorder by lowering the energy needed to trigger a therapeutic seizure.
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APGO automated insulin delivery with the TouchCare Nano patch pump for adults with type 1 diabetes
This study will test whether the APGO algorithm in the Medtrum TouchCare Nano patch pump improves blood glucose control and is safe for adults with type 1 diabetes in everyday use.
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Five-year overview of donated human milk amounts and quality at a Czech hospital milk bank
This project looks at donated breast milk from women who gave to the České Budějovice hospital milk bank between 2021 and 2025 to see if maternal and birth factors are linked to how much milk is donated and to routine measures of milk quality.
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Long-term recovery and vaccination cost-effectiveness for tick-borne encephalitis in the Czech Republic
This project follows children and adults hospitalized with tick-borne encephalitis in the Czech Republic to see how they recover, which symptoms persist, and to estimate the health and economic benefits of vaccination.
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External negative pressure during lighter-invasive surfactant administration
This study tests whether applying gentle external suction during LISA helps preterm babies breathe better and makes surfactant delivery safer.
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SaCoVLM™ video laryngeal mask for airway management by military medics
This project will test whether the SaCoVLM™ video laryngeal mask helps military medics with limited intubation experience manage airways safely during simulation and in sedated elective surgery patients.
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Improving how adults with COPD and asthma stick to and use their inhalers
This project will test whether a mobile/web app plus targeted training helps adults with COPD or asthma use their inhalers correctly and keep taking their inhaled medicines.
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Testing brain vestibular centers after vestibular schwannoma surgery with MRI
We’re testing whether brain areas that control balance light up differently in people after vestibular schwannoma surgery compared to healthy individuals using MRI.
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Residual and recurrent carotid narrowing after endarterectomy with primary closure
The study will test how often and when carotid narrowing comes back after elective carotid endarterectomy with primary closure in adults.
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Effects of pelvic organ diseases on endometrial receptivity in infertile women
This study is trying to see how conditions like adenomyosis, fibroids, and endometriosis affect the ability of the uterus to support pregnancy in women who are having trouble getting pregnant.
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Hyperinflammation and High Ferritin in Critically Ill Patients
This study looks at critically ill patients with signs of high inflammation to see how their condition develops over time.
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Pulsed-field ablation of the posterior left atrium and mitral isthmus for non-paroxysmal AF
This tests the Varipulse pulsed-field ablation catheter for isolating pulmonary veins and treating the left atrial posterior wall and mitral isthmus in people with non-paroxysmal atrial fibrillation.
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Using artificial intelligence to improve oocyte and embryo quality assessment in fertility treatments
This study is testing whether using artificial intelligence can help improve the quality of eggs and embryos in fertility treatments like IVF to boost the chances of pregnancy.
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Observing symptoms in children with first-onset bronchial asthma
This study looks at how asthma shows up in kids and teens aged 3 to 18, especially if they have unusual symptoms like a chronic cough, to see if a specific questionnaire can help spot these cases better.
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Evaluating blood flow in pancreatic remnants after surgery using fluorescence
This study is testing if a special dye can help doctors see blood flow in the remaining part of the pancreas after surgery to predict the risk of complications like pancreatic fistulas in patients.
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Comparing pulsed-field ablation to a sham procedure for treating atrial fibrillation
This study is testing whether a new treatment called pulsed-field ablation can help people with atrial fibrillation feel better and improve their quality of life compared to a fake procedure.
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Understanding Muscle Regeneration in ICU Survivors
This study is trying to understand how muscle weakness happens in people who have survived serious illnesses by looking at special cells that help muscles heal.
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Comparing two surgical methods for pelvic organ prolapse repair
This study is testing two different surgical methods to see which one works better for women over 50 with pelvic organ prolapse.
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Using sevoflurane to treat chronic leg ulcers
This study tests if using sevoflurane on painful leg ulcers can help reduce pain and improve healing compared to a regular rinse solution.
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Improving resilience in gynaecological cancer patients before surgery
This study is testing whether a special program that includes exercise, mental support, and nutrition can help women with advanced ovarian and frail endometrial cancer feel better and recover faster before their surgery.
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Understanding immune response in sepsis and septic shock
This study looks at how the immune system reacts in people with sepsis and septic shock to see if understanding these responses can help improve treatment in the future.
Quick answers
How many clinical trials run by Charles University, Czech Republic are recruiting right now?
27, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in Czechia (27 trials), Slovakia (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 2, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.