Using artificial intelligence to improve oocyte and embryo quality assessment in fertility treatments
Official title: Scanning the Meiotic Spindle in Assisted Reproductive Techniques to Assess Oocyte Quality and Embryo Ploidy Evaluated by Artificial Intelligence (SMARTAI Study)
Run by Charles University, Czech Republic · NCT06539104 · Data updated 2026-11-12
This study is testing whether using artificial intelligence can help improve the quality of eggs and embryos in fertility treatments like IVF to boost the chances of pregnancy.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 49 Years |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Charles University, Czech Republic Academic / other |
| Locations | 4 sites (Prague and 3 other locations) |
| Status | Recruiting |
| Started | January 5, 2024 |
| Main results expected | December 31, 2027 |
| Study ends | March 31, 2028 |
| Registry record updated | January 22, 2025 |
| Trial ID | NCT06539104 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study include individuals undergoing intracytoplasmic sperm injection (ICSI) and preimplantation genetic testing.
✕Probably not a fit
Patients with gynecological diseases or genetic disorders may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to enhance the success rates of assisted reproductive techniques, particularly in vitro fertilization (IVF), by applying artificial intelligence (AI) to assess oocyte quality and embryo ploidy. The study will analyze meiotic spindle imaging and other factors to predict pregnancy success probabilities. By automating the evaluation of oocyte and embryo development through advanced imaging and machine learning techniques, the study seeks to improve embryo selection and reduce the costs associated with fertility treatments.
Why it matters
Potential benefit: If successful, this approach could significantly increase the efficiency and success rates of fertility treatments for patients struggling with infertility.
How similar studies have gone: While the application of AI in reproductive medicine is emerging, this specific approach to assessing oocyte quality and embryo ploidy is relatively novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Intracytoplasmatic Sperm Injection * Preimplantation genetic testing * Time lapse embryo record * Singned informed consent Exclusion Criteria: * Gynecological diseases * Genetical diseases of parents
Where it's running
-
General University Hospital in Prague
Prague, Czechia Recruiting -
Czech Technical University in Prague
Prague, Czechia Recruiting -
Institute of Physics AS CR
Prague, Czechia Recruiting -
Biocev As Cr
Vestec, Czechia Recruiting
Study contacts
- Study coordinator: Jaromir Masata, MD
- Email: masata@volny.cz
- Phone: +420603444662
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.