Using artificial intelligence to improve oocyte and embryo quality assessment in fertility treatments
Scanning the Meiotic Spindle in Assisted Reproductive Techniques to Assess Oocyte Quality and Embryo Ploidy Evaluated by Artificial Intelligence (SMARTAI Study)
This study is testing whether using artificial intelligence can help improve the quality of eggs and embryos in fertility treatments like IVF to boost the chances of pregnancy.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years to 49 Years |
| Sex | All |
| Sponsor | Charles University, Czech Republic Academic / other |
| Locations | 4 sites (Prague and 3 other locations) |
| Trial ID | NCT06539104 on ClinicalTrials.gov |
What this trial studies
This observational study aims to enhance the success rates of assisted reproductive techniques, particularly in vitro fertilization (IVF), by applying artificial intelligence (AI) to assess oocyte quality and embryo ploidy. The study will analyze meiotic spindle imaging and other factors to predict pregnancy success probabilities. By automating the evaluation of oocyte and embryo development through advanced imaging and machine learning techniques, the study seeks to improve embryo selection and reduce the costs associated with fertility treatments.
Who should consider this trial
Good fit: Ideal candidates for this study include individuals undergoing intracytoplasmic sperm injection (ICSI) and preimplantation genetic testing.
Not a fit: Patients with gynecological diseases or genetic disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly increase the efficiency and success rates of fertility treatments for patients struggling with infertility.
How similar studies have performed: While the application of AI in reproductive medicine is emerging, this specific approach to assessing oocyte quality and embryo ploidy is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Intracytoplasmatic Sperm Injection * Preimplantation genetic testing * Time lapse embryo record * Singned informed consent Exclusion Criteria: * Gynecological diseases * Genetical diseases of parents
Where this trial is running
Prague and 3 other locations
- General University Hospital in Prague — Prague, Czechia (Recruiting)
- Czech Technical University in Prague — Prague, Czechia (Recruiting)
- Institute of Physics AS CR — Prague, Czechia (Recruiting)
- Biocev As Cr — Vestec, Czechia (Recruiting)
Study contacts
- Study coordinator: Jaromir Masata, MD
- Email: masata@volny.cz
- Phone: +420603444662
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.