Clinical trial Recruiting at 4 sites Observational Ages 18 to 49

Using artificial intelligence to improve oocyte and embryo quality assessment in fertility treatments

Official title: Scanning the Meiotic Spindle in Assisted Reproductive Techniques to Assess Oocyte Quality and Embryo Ploidy Evaluated by Artificial Intelligence (SMARTAI Study)

Run by Charles University, Czech Republic · NCT06539104 · Data updated 2026-11-12

This study is testing whether using artificial intelligence can help improve the quality of eggs and embryos in fertility treatments like IVF to boost the chances of pregnancy.

Quick facts

Study typeObservational
Ages18 Years to 49 Years
SexAll
Enrollment1000 (estimated)
SponsorCharles University, Czech Republic
Academic / other
Locations4 sites (Prague and 3 other locations)
StatusRecruiting
StartedJanuary 5, 2024
Main results expectedDecember 31, 2027
Study endsMarch 31, 2028
Registry record updatedJanuary 22, 2025
Trial IDNCT06539104 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study include individuals undergoing intracytoplasmic sperm injection (ICSI) and preimplantation genetic testing.

Probably not a fit

Patients with gynecological diseases or genetic disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to enhance the success rates of assisted reproductive techniques, particularly in vitro fertilization (IVF), by applying artificial intelligence (AI) to assess oocyte quality and embryo ploidy. The study will analyze meiotic spindle imaging and other factors to predict pregnancy success probabilities. By automating the evaluation of oocyte and embryo development through advanced imaging and machine learning techniques, the study seeks to improve embryo selection and reduce the costs associated with fertility treatments.

Why it matters

Potential benefit: If successful, this approach could significantly increase the efficiency and success rates of fertility treatments for patients struggling with infertility.

How similar studies have gone: While the application of AI in reproductive medicine is emerging, this specific approach to assessing oocyte quality and embryo ploidy is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Intracytoplasmatic Sperm Injection
* Preimplantation genetic testing
* Time lapse embryo record
* Singned informed consent

Exclusion Criteria:

* Gynecological diseases
* Genetical diseases of parents

Where it's running

  • General University Hospital in Prague
    Prague, Czechia
    Recruiting
  • Czech Technical University in Prague
    Prague, Czechia
    Recruiting
  • Institute of Physics AS CR
    Prague, Czechia
    Recruiting
  • Biocev As Cr
    Vestec, Czechia
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.