Hyperinflammation and High Ferritin in Critically Ill Patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational analysis follows adults with critical illness and hyperinflammation to describe their clinical trajectories and inflammatory patterns. Data from patients admitted between 2020 and 2024 at the Charles University Faculty of Medicine and Teaching Hospital in Pilsen will be examined to identify ferritin levels and inflammatory syndrome characteristics. The goal is to understand how hyperinflammation correlates with outcomes in sepsis and related critical illness. No intervention is applied; the study relies on existing medical records and observational data. Researchers will describe trajectories and phenotypes to inform future research and care strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* critically ill patients
* admission between 01.01.2020 and 31.12.2024 (5yrs)

Exclusion Criteria:

* none

Where it's running

• Faculty of Medicine and Teaching Hospital, Charles University
  Pilsen, Czech Republic, Czechia Recruiting

Study contacts

• Principal investigator: Thomas Karvunidis, MD, PhD — Faculty of Medicine and Teaching Hospital, Charles University, Pilsen, Czech Republic
• Study coordinator: Thomas Karvunidis, MD, PhD
• Email: karvunidist@fnplzen.cz
• Phone: +420776160620

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.