Using sevoflurane to treat chronic leg ulcers

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of topical sevoflurane in treating painful, non-healing leg ulcers. Patients will be randomly assigned to receive either sevoflurane or a standard rinse solution during their wound treatment. The study will monitor pain intensity, microbial colonization, and the healing process over a period of five days. The primary focus is on pain relief, with secondary outcomes related to ulcer healing and microbial management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with painful (pain intensity on the numerical scale NRS 0-10 is NRS\>4) non- healing tibial venous ulcers

Exclusion Criteria:

* Allergy to sevoflurane
* Inability to understand the pain-intensity questionnaire

Where it's running

• Faculty Hospital Kralovske Vinohrady
  Prague, Czechia Recruiting

Study contacts

• Principal investigator: Jiří Málek, M.D. — 3rd Medical Faculty of Charles University
• Study coordinator: Jiri Malek, M.D.
• Email: malekj@fnkv.cz
• Phone: +4202671622461

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Using human placental membrane wraps with regular wound care to help heal stubborn diabetic foot and venous leg ulcers

  This trial tests whether adding one of four human placental membrane wraps to standard wound care helps people with nonhealing diabetic foot or venous leg ulcers heal faster and more completely than standard care alone.

  Recruiting Phase 4 BioLab Holdings · Philidelphia, Pennsylvania · NCT07089602

• Evaluating new treatments for nonhealing diabetic foot and venous leg ulcers.

  This study is testing whether new treatments for stubborn diabetic foot and leg ulcers can help people heal better when combined with standard care compared to just standard care alone.

  Recruiting Phase 4 Tiger Biosciences, LLC. · Monroeville, Pennsylvania · NCT06826339

• Evaluating human placental membrane products for treating nonhealing diabetic foot and venous leg ulcers

  This study is testing whether using human placental products along with regular care can help people with stubborn diabetic foot and leg ulcers heal better.

  Recruiting C5 Biomedical · Metairie, Louisiana · NCT06674980

• Evaluating new treatments for diabetic foot and venous leg ulcers

  This study is testing different new treatments for stubborn diabetic foot and leg ulcers to see if they help heal better than the standard care alone.

  Recruiting Stability Biologics · Circleville, Ohio · NCT06560502

• Using music therapy to reduce pain from leg ulcer care

  This study tests if music therapy can help reduce pain for adults getting treatment for leg ulcers.

  Recruiting University Hospital Center of Martinique · Fort-de-France · NCT06153589

• Registry of Chronic Wounds and Ulcers

  This study collects information from patients with chronic wounds and ulcers to see how well different treatments are working and to improve the quality of wound care.

  Recruiting U.S. Wound Registry · The Woodlands, Texas · NCT02280733

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.