Testing brain vestibular centers after vestibular schwannoma surgery with MRI
Official title: Mapping of Vestibular Center Activation Using fMRI in Patients With Vestibular Schwannoma
Run by Charles University, Czech Republic · NCT07130851 · Data updated 2026-11-12
We’re testing whether brain areas that control balance light up differently in people after vestibular schwannoma surgery compared to healthy individuals using MRI.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Charles University, Czech Republic Academic / other |
| Locations | 1 site (Prague) |
| Status | Recruiting |
| Started | June 1, 2025 |
| Main results expected | December 30, 2027 |
| Study ends | June 20, 2029 |
| Registry record updated | October 22, 2026 |
| Trial ID | NCT07130851 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with a history of unilateral vestibular schwannoma resection eligible for fMRI and without contraindications to MRI.
✕Probably not a fit
Individuals without vestibular symptoms or those unable to complete MRI or vestibular exams may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study uses functional MRI to visualize activation of vestibular centers in the brain after unilateral vestibular loss from vestibular schwannoma resection. Participants include patients with unilateral vestibular damage and healthy controls who will undergo MRI while completing questions and vestibular exams. The goal is to see if postoperative treatment can modify activation patterns, and to compare patients with controls. Researchers will analyze fMRI data alongside clinical and questionnaire findings to understand central compensation after surgery.
Why it matters
Potential benefit: If successful, findings could improve understanding of brain balance centers and guide rehabilitation after vestibular schwannoma surgery.
How similar studies have gone: Previous studies have demonstrated detectable vestibular-related brain activation with fMRI in various vestibular conditions, supporting this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * vestibular schwannoma Exclusion Criteria: * claustrophobia, visual impairment
Where it's running
-
Department of Otorhinolaryngology and Head and Neck Surgery, 1st Medical Faculty Charles University and University Hospital Motol
Prague, Czechia Recruiting
Study contacts
- Study coordinator: Marketa Bonaventurova, MD
- Email: marketa.bonaventurova@fnmotol.cz
- Phone: +420732766103
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.