Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Testing brain vestibular centers after vestibular schwannoma surgery with MRI

Official title: Mapping of Vestibular Center Activation Using fMRI in Patients With Vestibular Schwannoma

Run by Charles University, Czech Republic · NCT07130851 · Data updated 2026-11-12

We’re testing whether brain areas that control balance light up differently in people after vestibular schwannoma surgery compared to healthy individuals using MRI.

More Vestibular Schwannoma trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment40 (estimated)
SponsorCharles University, Czech Republic
Academic / other
Locations1 site (Prague)
StatusRecruiting
StartedJune 1, 2025
Main results expectedDecember 30, 2027
Study endsJune 20, 2029
Registry record updatedOctober 22, 2026
Trial IDNCT07130851 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with a history of unilateral vestibular schwannoma resection eligible for fMRI and without contraindications to MRI.

Probably not a fit

Individuals without vestibular symptoms or those unable to complete MRI or vestibular exams may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study uses functional MRI to visualize activation of vestibular centers in the brain after unilateral vestibular loss from vestibular schwannoma resection. Participants include patients with unilateral vestibular damage and healthy controls who will undergo MRI while completing questions and vestibular exams. The goal is to see if postoperative treatment can modify activation patterns, and to compare patients with controls. Researchers will analyze fMRI data alongside clinical and questionnaire findings to understand central compensation after surgery.

Why it matters

Potential benefit: If successful, findings could improve understanding of brain balance centers and guide rehabilitation after vestibular schwannoma surgery.

How similar studies have gone: Previous studies have demonstrated detectable vestibular-related brain activation with fMRI in various vestibular conditions, supporting this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* vestibular schwannoma

Exclusion Criteria:

* claustrophobia, visual impairment

Where it's running

  • Department of Otorhinolaryngology and Head and Neck Surgery, 1st Medical Faculty Charles University and University Hospital Motol
    Prague, Czechia
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.