Observing symptoms in children with first-onset bronchial asthma

Prospective Multicentre Study on Symptoms in First-onset Bronchial Asthma in Children and Adolescents

Charles University, Czech Republic · NCT06201494

This study looks at how asthma shows up in kids and teens aged 3 to 18, especially if they have unusual symptoms like a chronic cough, to see if a specific questionnaire can help spot these cases better.

Quick facts

Study typeObservational
Enrollment80 (estimated)
Ages3 Years to 18 Years
SexAll
SponsorCharles University, Czech Republic (other)
Locations1 site (Prague)
Trial IDNCT06201494 on ClinicalTrials.gov

What this trial studies

This study investigates the prevalence of both typical and atypical symptoms of bronchial asthma in children and adolescents aged 3 to 18 years. It aims to identify cases where asthma may present with less common symptoms such as chronic cough or recurrent pneumonia, which are often overlooked in standard diagnostic criteria. The study will also evaluate the effectiveness of the ISAAC questionnaire in detecting these symptoms. By focusing on a broader range of symptoms, the research seeks to improve the understanding and management of asthma in pediatric patients.

Who should consider this trial

Good fit: Ideal candidates for this study are children aged 3 to 18 years experiencing respiratory symptoms such as cough, shortness of breath, or recurrent pneumonia.

Not a fit: Patients with other chronic respiratory or significant systemic diseases that may cause respiratory symptoms are unlikely to benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to better diagnosis and management of asthma in children, particularly those presenting with atypical symptoms.

How similar studies have performed: While there is ongoing research into asthma symptoms, this study's focus on atypical presentations is relatively novel and may provide new insights into asthma diagnosis.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

\- Child 3 - 18 years old, first evaluation in pulmonary outpatient clinic for any of the following respiratory symptoms: cough, shortness of breath, chest tightness, wheezing, recurrent lower respiratory tract and lung infections, dyspnoea of any type, pathological listening findings.

Exclusion Criteria:

* Other documented chronic respiratory, cardiovascular, neurological, genetic, infectious, metabolic disease, significant immaturity or other disease that may be accompanied by respiratory symptoms.

Where this trial is running

Prague

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Asthma, Asthma in Children, Dyspnea, Cough, Pneumonia, Wheezing, Shortness of Breath, Chest Tightness

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.