Endometriosis affecting the urinary tract: long-term outcomes and kidney function

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study follows adults with deep endometriosis involving the urinary tract to understand long-term outcomes and changes in renal function. Participants are grouped based on surgical history and current need for surgery due to hydronephrosis or ureteral stenosis. The study collects data on kidney function, anatomy, and patient outcomes to better inform treatment decisions for ureteral endometriosis. No interventional treatment is specified in the protocol beyond observational assessments. The lead sponsor is Charles University in the Czech Republic, with data collected at General University Hospital in Prague.

Why it matters

Who can join: the full rules

Inclusion Criteria:• age ≥ 18 years;

* hydronephrosis caused by DE-related ureteral stenosis;
* for Group F: a history of surgical treatment of ureteral endometriosis (ureterolysis, ureteroureterostomy, UCNA) at our center at least 24 months previously;
* for Group S: indication for surgical treatment because of hydronephrosis or clinically significant ureteral stenosis;
* signed informed consent.

Exclusion Criteria:• pregnancy;

* malignancy;
* congenital uropathy;
* other renal diseases;
* inability to undergo dynamic renal scintigraphy (e.g., allergy to the radiopharmaceutical or severe comorbidities precluding the examination);
* previous urinary tract surgery unrelated to ureteral endometriosis that could substantially confound the assessment of renal function.

Where it's running

• General University in Prague
  Prague, Czechia Recruiting

Study contacts

• Study coordinator: Kristýna HLinecká, MD PhD
• Email: Kristyna.Hlinecka2@vfn.cz
• Phone: +420605413210

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.