Condition

Sedation and Analgesia clinical trials and research

• 10Clinical trials
• 1NIH research projects
• 7Countries

Newest Sedation and Analgesia clinical trials

All recruiting trials (10)

• Ketamine-Propofol vs Dexmedetomidine-Propofol Sedation for Pediatric Cardiac Catheterization

  This study tests two sedative combinations to see which is safer and more effective for children 2–12 undergoing device closure of simple left-to-right heart shunts.

  Recruiting Phase 1 Ain Shams University · Cairo · NCT07669012

• Impact of Anesthesia on Inflammation and NETosis During HCC Ablation

  This study tests whether a propofol–fentanyl anesthesia plan with lidocaine during radiofrequency ablation for hepatocellular carcinoma affects inflammation and NETosis in patients with small tumors.

  Recruiting Iuliu Hatieganu University of Medicine and Pharmacy · Cluj-Napoca, Cluj · NCT07657897

• IR-led deep ketamine sedation for select image-guided procedures

  We will try deep ketamine sedation instead of general anesthesia for adults having certain image-guided interventional radiology procedures.

  Recruiting Phase 1/2 CAMC Health System · Charleston, West Virginia · NCT07443254

• Cannabis use and IV sedation during wisdom tooth removal

  This project will see if people who use cannabis need different IV sedative doses or have different vital signs and breathing during wisdom tooth removal compared with people who don't use cannabis.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07423195

• Brain‑wave and pain‑signal monitoring during anesthesia for ERCP to map opioid and sedative effects

  This trial will test whether continuous brain‑wave (EEG/PSI) and heart‑rate variability (ANI) monitoring during targeted infusions of opioids and sedatives can show how those drugs interact in people having ERCP under general anesthesia.

  Recruiting China Medical University Hospital · Miaoli · NCT07211828

• How common pain is in adults on mechanical ventilators in intensive care units

  The researchers will measure how often adults on invasive mechanical ventilation in ICUs experience pain and which clinical factors are linked to it.

  Recruiting at 4 sites Centro Universitário Augusto Motta · Rio de Janeiro, Rio de Janeiro and 3 other locations · NCT07182851

• No continuous sedation versus daily sedation interruption for ventilated COPD patients

  This compares no continuous sedation to daily sedation breaks to see which approach gives more ventilator-free days for adults with COPD on a breathing machine.

  Recruiting Benha University · Banhā, Qalyubia Governorate · NCT07146698

• Co-designed pain and sedation protocol for adults on ECMO

  This project will test a co-designed pain and sedation plan to see if it's acceptable for adults receiving ECMO and similar ventilated ICU patients.

  Recruiting Guy's and St Thomas' NHS Foundation Trust · London, London · NCT07032987

• Improving pain control for children on breathing machines

  This trial tests whether giving IV acetaminophen and/or IV ketorolac can reduce pain and the need for opioids in children aged 2 months to 17½ years who are on mechanical ventilation for acute respiratory failure.

  Recruiting at 15 sites Phase 3 Weill Medical College of Cornell University · Little Rock, Arkansas and 15 other locations · NCT06994442

• Comparing Remimazolam and Midazolam for Sedation in Critically Ill Patients on Ventilators

  This study is testing if a new sedative called remimazolam can help critically ill patients on ventilators spend less time on the machine compared to the standard sedative midazolam.

  Recruiting Zhujiang Hospital · Guangzhou, Guangdong · NCT05160987

NIH-funded research (1)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Improving sedation and pain management for critically ill children

  This study is looking at how to give the right amount of medicine to help kids feel less pain and anxiety during tough medical procedures, so they can recover better and stay safe while getting the care they need.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-10802191

Related topics

Quick answers

How many Sedation and Analgesia clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (3 trials), Egypt (2 trials), Taiwan (1 trial), Brazil (1 trial), Romania (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 1, Phase 3: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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