Condition

Postpartum Hemorrhage clinical trials and research

• 20Clinical trials
• 18NIH research projects
• 1New in 30 days
• 15Countries

Newest Postpartum Hemorrhage clinical trials

All recruiting trials (20)

• Long-term outcomes after vacuum-induced tamponade for postpartum hemorrhage

  This study will look at women who had postpartum hemorrhage treated with vacuum-induced tamponade at a Zurich hospital to see how they fared over time, including future pregnancies and fertility.

  Recruiting University of Zurich · Zurich, Canton of Zurich · NCT07885072

• Calcium Gluconate After Birth to Reduce Blood Loss in Vaginal Delivery

  This study tests whether giving calcium gluconate right after the baby is born can help reduce blood loss for people having a vaginal delivery.

  Recruiting Rambam Health Care Campus · Haifa · NCT07714902

• Carbetocin Alone vs Carbetocin Plus Oxytocin After Elective Cesarean Delivery

  This study tests whether giving carbetocin by itself after an elective cesarean is just as good as adding a supplemental oxytocin infusion.

  Recruiting Phase 4 Mansoura University · Buraidah, Al-Qassim Region · NCT07636421

• Simulation-based postpartum hemorrhage training to boost anesthesiology team performance

  Senior anesthesiology residents will try a high-fidelity simulation program for postpartum hemorrhage to see if it improves how their teams perform during obstetric emergencies.

  Recruiting Hacettepe University · Ankara, Ankara · NCT07519252

• Carbetocin to prevent heavy bleeding after twin birth

  This trial tests whether a single dose of carbetocin given after the second twin is born reduces heavy bleeding compared with standard oxytocin in people delivering twins.

  Recruiting Phase 4 Sheba Medical Center · Ramat Gan · NCT07401524

• Draining the umbilical cord after birth to lower postpartum bleeding

  This trial tests whether draining blood from the cut umbilical cord right after birth lowers heavy bleeding after delivery in women having a term vaginal birth.

  Recruiting at 2 sites Universidad Nacional Autonoma de Honduras · Tegucigalpa, Francisco Morazán Department and 1 other locations · NCT07401160

• Opening the maternal cord clamp to speed placental delivery and reduce postpartum bleeding

  This test will see if opening the clamp on the mother's end of the cut umbilical cord helps the placenta come out sooner and reduces bleeding in low-risk, full-term women after a vaginal birth.

  Recruiting Saglik Bilimleri Universitesi Gulhane Tip Fakultesi · Zonguldak, Zonguldak/Centre · NCT07279545

• Tranexamic acid use for heavy bleeding after cesarean delivery

  This study will test whether wider use of tranexamic acid for heavy postpartum bleeding during cesarean delivery is linked to better outcomes for mothers and babies.

  Recruiting Mahidol University · Bangkoknoi, Bangkok · NCT07278037

• Non-invasive zinc protoporphyrin screening for iron deficiency in pregnancy

  This project tests a handheld device that measures zinc protoporphyrin through the lower lip to detect iron deficiency in pregnant and recently postpartum people.

  Recruiting Wuerzburg University Hospital · Würzburg, Bavaria · NCT07083492

• Temporary abdominal aortic compression with the AAJT-S for severe postpartum bleeding

  This will try using the AAJT-S abdominal tourniquet to stop severe postpartum bleeding in women whose bleeding does not stop with usual treatments.

  Recruiting LLC UkrMedGroup · Zaporizhzhya · NCT07034924

• THUMB care package to reduce bleeding during and after caesarean section

  This project tests a perioperative care package called the 'Rule of THUMB' to reduce bleeding in people having a caesarean section.

  Recruiting University of Cape Town · Cape Town · NCT07005349

• Using tranexamic acid to prevent postpartum hemorrhage in women with autoimmune diseases

  This study is testing if tranexamic acid can help prevent heavy bleeding after childbirth in women with autoimmune diseases who are having a cesarean delivery.

  Recruiting Phase 4 RenJi Hospital · Shanghai, Shanghai Municipality · NCT06754371

• Reducing postpartum blood loss with coagulation factor XIII

  This study is testing if giving a treatment called coagulation factor XIII can help reduce heavy bleeding after childbirth in women who have had a vaginal delivery.

  Recruiting at 8 sites Phase 4 University of Zurich · Geneva, Canton of Geneva and 8 other locations · NCT06481995

• Comparing uterotonic drugs to prevent postpartum bleeding after cesarean delivery

  This study tests if giving extra doses of carbetocin or trying other medications can help women who have had a cesarean delivery prevent heavy bleeding by improving how well their uterus contracts.

  Recruiting Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Toronto, Ontario · NCT06285409

• Effects of medications on uterine contractions during cesarean delivery in diabetic patients

  This study is testing how certain medications for low blood pressure during cesarean deliveries affect uterine contractions in women with Type II and gestational diabetes.

  Recruiting Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Toronto, Ontario · NCT06285396

• Using tranexamic acid to prevent heavy bleeding after childbirth in at-risk women

  This study is testing if giving tranexamic acid before delivery can help prevent heavy bleeding after childbirth in women who are at higher risk.

  Recruiting Phase 3 London School of Hygiene and Tropical Medicine · Mbeya · NCT05562609

• New method to control bleeding after childbirth

  This study is testing a new device called the Jada® System to see if it can help women who are bleeding heavily after childbirth more effectively than standard treatments.

  Recruiting at 2 sites Women and Infants Hospital of Rhode Island · Kumasi, Ashanti Region and 1 other locations · NCT05382403

• Determining the best oxytocin dose for cesarean delivery

  This study is testing the lowest amount of oxytocin needed to help women having a cesarean delivery have better uterine contractions and reduce bleeding after childbirth.

  Recruiting Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Toronto, Ontario · NCT05290129

• Using two medications to prevent postpartum hemorrhage

  This study tests if giving two medications together can better prevent heavy bleeding after childbirth in women delivering at Stony Brook University Hospital.

  Recruiting Phase 3 Stony Brook University · Stony Brook, New York · NCT05245227

• Using tranexamic acid to reduce blood loss after cesarean delivery in women with placenta previa

  This study tests if giving tranexamic acid after a cesarean delivery can help reduce blood loss in women with placenta previa.

  Recruiting Phase 3 University Hospital, Bordeaux · Bordeaux · NCT04304625

NIH-funded research (18)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Wearable tech to track blood loss during childbirth

  A wearable device monitors cardiovascular signals to detect postpartum hemorrhage early so clinicians can act quickly to protect mothers.

  NIH research Washington University · Saint Louis, United States · NIH-11627926

• Maternal Postpartum Monitoring with a Wearable Sensor (MOMS)

  A wearable system called MOMS will continuously monitor multiple physiological signals in pregnant people to detect postpartum hemorrhage earlier than standard vital signs.

  NIH research University of California-Irvine · Irvine, United States · NIH-11536966

• AI-powered real-time postpartum hemorrhage risk predictor in clinical care

  A real-time AI tool integrated into electronic health records helps identify women at risk for postpartum hemorrhage so clinicians can intervene earlier.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11448238

• Targeting Ubiquitination to Improve Uterotonic Therapies in Postpartum Hemorrhage

  A new approach aims to boost uterine contractions during childbirth and after delivery by understanding how a hormone receptor is regulated, potentially reducing postpartum hemorrhage risk.

  NIH research Washington University · Saint Louis, United States · NIH-11442951

• Personalized Postpartum Bleeding Risk Prediction with Machine Learning and Genetic Scores

  This grant aims to create a personalized tool that predicts a mother’s risk of postpartum hemorrhage using machine learning and her genetic information.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11419168

• OPTIMUM OB-TXA: Timing, route, and dose of tranexamic acid to prevent postpartum bleeding before cord clamping

  Aims to find the best time, method, and amount of tranexamic acid given before cord clamping to prevent postpartum hemorrhage in new mothers and protect babies.

  NIH research Inova Health Care Services · Fairfax, UNITED STATES · NIH-11404879

• Simulation to strengthen obstetricians' hands-on skills for postpartum hemorrhage

  A multicenter program uses realistic obstetric simulations to help OB attendings perform critical maneuvers like Bakri balloon placement and suturing techniques during postpartum hemorrhage.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11372119

• Oxytocin sensitivity and postpartum bleeding risk markers

  This project looks at genetic and epigenetic clues to predict and prevent heavy bleeding after childbirth.

  NIH research University of Arizona · Tucson, United States · NIH-11362224

• Wearable monitor to detect blood loss after childbirth

  This project will create a wearable, light-based device that continuously estimates blood loss in people who have just given birth so heavy bleeding can be found sooner.

  NIH research Washington University · Saint Louis, United States · NIH-11362125

• Vasowatch: Predicting postpartum hemorrhage with maternal heart data

  A new monitoring system uses heart-rate data to predict postpartum hemorrhage hours before delivery, helping care teams act sooner.

  NIH research Vasowatch LLC · Philadelphia, United States · NIH-11316152

• Advanced hemostatic hydrogel for postpartum hemorrhage control

  A new biodegradable hydrogel adhesive called HemoMax-PPH is being developed to help stop severe postpartum bleeding more effectively, potentially saving mothers in both high- and low-income countries.

  NIH research Limax Biosciences INC · Somerville, United States · NIH-11315884

• Best timing, route, and dose of tranexamic acid before cord clamp to prevent heavy bleeding after childbirth

  This project tests different ways of giving tranexamic acid to help prevent heavy bleeding in people during and after childbirth.

  NIH research Inova Health Care Services · Fairfax, UNITED STATES · NIH-11145713

• Improving Doctor Skills for Severe Bleeding After Childbirth

  This project helps doctors practice managing severe bleeding after childbirth to make care safer for mothers.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11109433

• Understanding Oxytocin and Postpartum Bleeding

  This research looks at how genetics and other factors might make some mothers more likely to experience heavy bleeding after childbirth, even when given oxytocin.

  NIH research University of Arizona · Tucson, United States · NIH-11106045

• A wearable device to detect early signs of postpartum hemorrhage

  This study is testing a new wearable device that helps new moms keep an eye on their blood flow to catch early signs of postpartum hemorrhage, so they can get quick help if needed.

  NIH research Washington University · Saint Louis, United States · NIH-10919207

• New method to control severe bleeding after childbirth.

  This study is looking at a new way to help women who experience heavy bleeding after giving birth by using a special vacuum method along with a balloon treatment, and it aims to see if this approach works better than the usual care.

  NIH research Women and Infants Hospital-Rhode Island · Providence, United States · NIH-10908538

• Finding the best way to use tranexamic acid to prevent postpartum bleeding

  This study is looking at the best ways to use a medication called tranexamic acid to help prevent heavy bleeding after childbirth, and it's for women who are having a baby vaginally, through a cesarean section, or who have obesity, so we can find the safest and most effective options for both moms and their babies.

  NIH research Inova Health Care Services · Fairfax, UNITED STATES · NIH-10903995

• Predicting postpartum bleeding risks using advanced algorithms and genetic information

  This study is working on a new tool to help predict the risk of heavy bleeding after childbirth, using advanced technology to look at both medical history and genetic information, so that new moms can get better care and support during and after delivery.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-10888319

Related topics

Quick answers

How many Postpartum Hemorrhage clinical trials are recruiting right now?

20, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 15 countries. The most sites are in Canada (3 trials), Israel (2 trials), Switzerland (2 trials), Turkey (Türkiye) (2 trials), Saudi Arabia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 4, Phase 3: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →