Condition

Iron Deficiency clinical trials and research

• 18Clinical trials
• 27NIH research projects
• 12Countries

Newest Iron Deficiency clinical trials

All recruiting trials (18)

• Iron status prediction in elderly with inflammation

  This study tests a model to tell true iron deficiency from inflammation-related anemia in people aged 75 and older who are hospitalized with inflammation.

  Recruiting Centre Hospitalier Régional d'Orléans · Orléans, Loiret · NCT07739524

• Lactoferrin with low-dose iron to boost iron levels and aerobic fitness in active women

  We will test whether taking lactoferrin with a small daily dose of iron helps raise iron stores and improve aerobic performance in menstruating women with low ferritin.

  Recruiting Lindenwood University · Saint Charles, Missouri · NCT07546591

• AI-guided risk alerts to help doctors spot iron deficiency

  This trial tests whether an AI risk alert shown to clinicians after a CBC helps them detect iron deficiency more often in adult outpatients.

  Recruiting China Medical University Hospital · Taichung · NCT07394088

• Intravenous iron infusion after transcatheter aortic valve implantation for people with iron deficiency

  This trial will test whether an intravenous iron infusion after TAVI helps people aged 65 and older with severe aortic stenosis and iron deficiency feel better and walk farther.

  Recruiting Phase 4 Erasmus Medical Center · Rotterdam, South Holland · NCT07370688

• Intravenous iron to improve exercise capacity and quality of life in pulmonary hypertension

  This trial will test whether intravenous ferric carboxymaltose can improve exercise ability and quality of life in adults with pulmonary hypertension who have iron deficiency.

  Recruiting Phase 4 Ziekenhuis Oost-Limburg · Aalst and 6 other locations · NCT07359599

• Preoperative IV iron for teens having spinal fusion to correct scoliosis

  This trial will try giving a single IV iron infusion before spinal fusion to see if it helps 10–19-year-olds with scoliosis and low iron by reducing blood transfusions and improving recovery.

  Recruiting Phase 2/3 Columbia University · New York, New York · NCT07217873

• Non-invasive zinc protoporphyrin screening for iron deficiency in pregnancy

  This project tests a handheld device that measures zinc protoporphyrin through the lower lip to detect iron deficiency in pregnant and recently postpartum people.

  Recruiting Wuerzburg University Hospital · Würzburg, Bavaria · NCT07083492

• Iron absorption and losses in young South African women with and without overweight or obesity

  This study tests whether young South African women with overweight or obesity absorb and lose iron differently than women without overweight by giving a labeled iron drink and following them for a year.

  Recruiting North-West University, South Africa · Potchefstroom, North West · NCT07081152

• Improving iron levels in young female endurance, intermittent, and power/strength athletes aged 16-35

  This trial will test whether different types and doses of oral iron supplements, taken every other day for 12 weeks, help young female athletes with low iron stores improve iron levels, gut health, and exercise performance while causing fewer stomach symptoms.

  Recruiting University of Calgary · Calgary, Alberta · NCT06942208

• Impact of maternal iron deficiency on child health

  This study looks at how a lack of iron in pregnant women affects the health of their children from birth to age 7.

  Recruiting Tampere University Hospital · Tampere, Pirkanmaa · NCT06879080

• Comparing low-dose and high-dose intravenous iron therapy for heart failure patients with iron deficiency

  This study is testing if giving heart failure patients with iron deficiency a higher dose of intravenous iron helps them exercise better than a lower dose.

  Recruiting Phase 4 China-Japan Friendship Hospital · Beijing, Beijing Municipality · NCT06427343

• Oral sucrosomial iron's effect on exercise and quality of life in heart failure patients

  This study is testing if a new type of oral iron can help people with heart failure and low iron feel better and exercise more easily compared to a placebo.

  Recruiting Phase 4 Azienda Ospedaliero, Universitaria Pisana · Pisa, Tuscany · NCT06270498

• Identifying Women at Risk for Placental Dysfunction

  This study is trying to see if a new tool can help identify pregnant women at risk for placental problems by looking at their health information and blood tests.

  Recruiting Oulu University Hospital · Oulu · NCT06115122

• Comparing two forms of iron supplementation during pregnancy

  This study is testing which of two types of iron supplements works better for pregnant people to improve their iron levels and overall health.

  Recruiting at 2 sites University of British Columbia · Vancouver, British Columbia and 1 other locations · NCT06014983

• Effects of Ferric Derisomaltose on Exercise Capacity and Quality of Life in Heart Failure Patients

  This study is testing if adding Ferric Derisomaltose to regular treatment can help people with heart failure and low iron feel better and exercise more easily.

  Recruiting Phase 4 China-Japan Friendship Hospital · Beijing, Beijing Municipality · NCT05971732

• Tracking iron distribution in the body after intravenous iron infusion

  This study is testing how intravenous iron infusions change iron levels in different parts of the body over time for people with iron deficiency.

  Recruiting University of Oxford · Oxford, Oxfordshire · NCT05609318

• Using ferric derisomaltose to improve recovery in gynecologic cancer surgery

  This study is testing if an iron treatment can help women with gynecologic cancer surgery recover better by improving their iron levels and reducing the need for blood transfusions.

  Recruiting Phase 3 AHS Cancer Control Alberta · Calgary, Alberta · NCT05407987

• Using Darbe and IV iron to reduce transfusions in preterm infants

  This study is testing if giving preterm infants a combination of a special medication and intravenous iron can help reduce the need for blood transfusions and support their growth and development better than regular oral iron.

  Recruiting Phase 2 University of Washington · Seattle, Washington · NCT05340465

NIH-funded research (27)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Teen Period app study to understand menstruation and iron deficiency in newly tapped teens

  A national study using a teen-friendly mobile app to track menstruation and identify factors linked to iron deficiency in girls who have just started menstruating.

  NIH research Research Inst Nationwide Children's Hosp · Columbus, United States · NIH-11466141

• Thyroid hormone and early brain development in iron-deficient kids

  This grant explores how thyroid hormone and iron deficiency in early life affect brain development and later ADHD-like behaviors in children.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11412452

• Iron‑deficiency anemia and its impact on brain function in late childhood

  This study looks at how iron-deficiency anemia in late childhood and adolescence may affect thinking skills and brain development in young females.

  NIH research Washington University · Saint Louis, United States · NIH-11394540

• Brain blood flow and oxygen use in adult iron deficiency anemia

  This study looks at how moderate iron deficiency anemia in adults affects brain blood flow, oxygen use, and thinking abilities, and whether iron treatment can reverse any problems.

  NIH research Children's Hospital of Los Angeles · Los Angeles, United States · NIH-11393318

• Machine learning to predict iron deficiency risk in babies based on mom’s stress during pregnancy

  A fast, data-driven approach uses a mother’s stress during pregnancy to help predict which babies might be at risk for iron deficiency anemia.

  NIH research Northeastern University · Boston, United States · NIH-11384738

• Iron deficiency and inflammation: how lack of iron worsens lung and kidney injury

  This NIH grant looks at how iron deficiency makes inflammatory organ injury worse, especially in lung and kidney, to help future patients who have anemia with inflammatory conditions.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11378189

• Iron deficiency and brain development in 3q29 deletion syndrome

  Researchers are studying how iron deficiency might influence neurodevelopmental outcomes in kids with a 3q29 deletion.

  NIH research Virginia Polytechnic Inst and St Univ · Blacksburg, United States · NIH-11372578

• Iron-deficiency anemia treatment plan for adults undergoing surgery

  Aimed at adults having surgery, this project tests a practical plan to identify and treat iron deficiency anemia to improve recovery and reduce complications.

  NIH research University of Chicago · Chicago, United States · NIH-11356890

• How the body absorbs iron from meat and other foods in rats to understand iron deficiency and overload

  A researcher is studying how the body absorbs iron from the diet, especially the differences between iron from meat and other sources, to better understand conditions like iron deficiency and iron overload in people.

  NIH research University of Florida · Gainesville, United States · NIH-11332718

• Newborn Iron Deficiency and its Long-Term Brain Effects

  A study exploring how iron deficiency in early life can affect a child’s brain development and long-term cognitive and emotional health.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11324638

• Understanding how low iron levels make inflammation worse

  This research explores how having low iron might make inflammation and tissue damage worse, especially in vital organs like the lungs and kidneys.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11184441

• How iron-deficiency anemia in later childhood affects the brain and thinking

  This project looks at girls and young women aged 12–21 with iron-deficiency anemia to see how it changes brain metabolism, blood flow, and thinking using cognitive tests and MRI scans.

  NIH research Washington University · Saint Louis, United States · NIH-11169048

• Predicting pregnancy and newborn iron-deficiency risk linked to stress during pregnancy

  This project uses computer models to predict which pregnant people and their newborns might develop iron-deficiency anemia after stress during pregnancy.

  NIH research Northeastern University · Boston, United States · NIH-11163567

• How iron-deficiency anemia affects adult brain blood flow, oxygen, and memory

  This project tests whether treating moderate iron-deficiency anemia can improve brain blood flow, oxygen use, and thinking in adult women.

  NIH research Children's Hospital of Los Angeles · Los Angeles, United States · NIH-11159407

• Understanding how stress during pregnancy affects iron deficiency anemia in mothers and infants

  This study is looking at how stress during pregnancy might affect iron levels in moms and their babies, especially for those from low-income and diverse backgrounds, to find better ways to prevent and treat iron deficiency anemia.

  NIH research Northeastern University · Boston, United States · NIH-11136629

• Investigating the effects of iron deficiency in newborns

  This study is looking at how not getting enough iron early in life can affect how babies and young kids think and learn, and it aims to find ways to help those who might be struggling because of it.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11136375

• Understanding how the body absorbs iron from food in different conditions.

  This study is looking at how our bodies take in heme iron from food, especially for people dealing with low iron levels or too much iron, to help improve treatments for conditions like anemia and hemochromatosis.

  NIH research University of Florida · Gainesville, United States · NIH-11081686

• Oral vs IV Iron in Pregnancy: A Larger Trial to Prevent Anemia and Transfusions

  This study tests whether IV iron during pregnancy can be better than oral iron at improving anemia and reducing the need for blood transfusions.

  NIH research Women and Infants Hospital-Rhode Island · Providence, United States · NIH-11057518

• Investigating how iron deficiency affects COPD patients

  This study is looking at how low iron levels might affect the health and exercise ability of people with COPD, and it hopes to find out if boosting iron levels can help improve their overall well-being and quality of life.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10988250

• Using AI to improve iron deficiency treatment in pregnant individuals

  This study is testing a new tool to help doctors better find and treat iron deficiency in pregnant people, especially those at higher risk for heavy bleeding after giving birth, to improve their health during and after pregnancy.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-10951600

• The link between iron deficiency and brain development in youth with anxiety and depression

  This study is looking at how low iron levels might impact the brain development of teenagers aged 10 to 17 who are dealing with anxiety and depression, using blood tests and brain scans to see how these factors are connected.

  NIH research Baylor College of Medicine · Houston, United States · NIH-10918304

• Investigating the link between iron deficiency and brain development in youth with anxiety and depression

  This study is looking at how low iron levels might impact the brain development of teenagers aged 10 to 17 who are dealing with anxiety and depression, and it hopes to find out if there's a link between iron in the body and how serious their symptoms are.

  NIH research Baylor College of Medicine · Houston, United States · NIH-10912306

• Investigating how iron deficiency anemia affects brain blood flow and cognition in adults

  This study is looking at how iron deficiency anemia affects thinking and memory in women aged 14-60, and it will see if getting more iron can help improve these brain functions.

  NIH research Children's Hospital of Los Angeles · Los Angeles, United States · NIH-10906226

• Effects of iron deficiency anemia on brain development in late childhood

  This study is looking at how iron deficiency anemia in girls aged 12 to 21 affects their brain development and thinking skills, and it will involve some tests and brain scans to see how their brains are working during this important time in their lives.

  NIH research Washington University · Saint Louis, United States · NIH-10881010

• Understanding iron deficiency in heart failure with preserved ejection fraction

  This study is looking at how low iron levels might affect people with heart failure who still have good heart function, focusing on how it impacts their ability to exercise and enjoy life, with the hope of finding better treatments to help them feel better.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-10867349

• A new device to measure hepcidin in urine for detecting iron deficiency in children and teens

  This study is testing a new, easy-to-use device that helps doctors quickly check for iron deficiency in kids and teens by measuring a substance in their urine, so they can get the help they need to grow and develop properly.

  NIH research Intrinsic Lifesciences, LLC · La Jolla, United States · NIH-10709598

• Iron deficiency during pregnancy affects brain development in the fetus

  This study is looking at how not getting enough iron during pregnancy might affect your baby's brain development, with the goal of finding ways to help improve brain health in children later on.

  NIH research University of Rochester · Rochester, United States · NIH-10436873

Related topics

Quick answers

How many Iron Deficiency clinical trials are recruiting right now?

18, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in Canada (3 trials), United States (3 trials), Finland (2 trials), China (2 trials), South Africa (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 5, Phase 3: 1, Phase 2: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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