Non-invasive zinc protoporphyrin screening for iron deficiency in pregnancy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, longitudinal observational study enrolling up to 500 participants to test a fluorescence-based device that measures zinc protoporphyrin (ZnPP) transcutaneously at the lower lip. Measurements will be taken once per trimester, at delivery, and about 2–3 months postpartum and compared with conventional blood-based iron markers. The study will analyze diagnostic agreement between non-invasive ZnPP and laboratory tests and track associations between iron status and outcomes such as postpartum depression, restless legs syndrome, obstetric complications, transfusion need, and quality of life. The protocol focuses on feasibility and diagnostic value of point-of-care non-invasive screening in an obstetric population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* any timepoint during or up to 3 months after pregnancy
* age ≥ 18 years
* written informed consent

Exclusion Criteria:

* previous participation in this study
* refusal of blood sampling
* incapacity to give informed consent

Where it's running

• University Hospital Würzburg
  Würzburg, Bavaria, Germany Recruiting

Study contacts

• Study coordinator: Peter Kranke, MD, MBA
• Email: kranke_p@ukw.de
• Phone: +4993120130050

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.