Advanced hemostatic hydrogel for postpartum hemorrhage control
Official title: Advanced Hemostatic Adhesive Hydrogel System for Postpartum Hemorrhage Control
Funded at Limax Biosciences INC · NIH-11315884 · Data updated 2026-11-12
A new biodegradable hydrogel adhesive called HemoMax-PPH is being developed to help stop severe postpartum bleeding more effectively, potentially saving mothers in both high- and low-income countries.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Limax Biosciences INC NIH-funded |
| Lab location | 1 site (Somerville, United States) |
| Project start | September 10, 2026 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $1,047,908 |
| NIH project number | 1R44HL184761-01 |
| Project ID | NIH-11315884 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients experiencing postpartum hemorrhage who would benefit from improved local hemostasis and sealant-based interventions.
✕Less likely to help
Patients with PPH where a hydrogel device is not appropriate or contraindicated may not benefit.
What this research studies
This project aims to advance a hydrogel adhesive that works with a balloon tamponade and suction system to rapidly seal bleeding sites in postpartum hemorrhage. It focuses on biocompatibility and large-animal testing to meet regulatory requirements for FDA 510(k) clearance. If successful, it could provide a more reliable and faster method to control PPH where current balloon-based devices fall short.
Why it matters
Potential benefit: If successful, the product could reduce maternal deaths from postpartum hemorrhage by improving hemostasis at the bleeding site.
How similar studies have gone: Preclinical studies have shown strong adhesion and compatibility; further animal studies and GLP testing are planned to support regulatory approval.
Where this research is happening
-
Limax Biosciences INC
Somerville, United States Active
Researchers
- Principal investigator: Freedman, Benjamin Ross — Limax Biosciences INC
- Study coordinator: Freedman, Benjamin Ross
Related research
Other NIH-funded projects on the same topics.
-
Wearable tech to track blood loss during childbirth
A wearable device monitors cardiovascular signals to detect postpartum hemorrhage early so clinicians can act quickly to protect mothers.
-
Maternal Postpartum Monitoring with a Wearable Sensor (MOMS)
A wearable system called MOMS will continuously monitor multiple physiological signals in pregnant people to detect postpartum hemorrhage earlier than standard vital signs.
-
AI-powered real-time postpartum hemorrhage risk predictor in clinical care
A real-time AI tool integrated into electronic health records helps identify women at risk for postpartum hemorrhage so clinicians can intervene earlier.
-
Targeting Ubiquitination to Improve Uterotonic Therapies in Postpartum Hemorrhage
A new approach aims to boost uterine contractions during childbirth and after delivery by understanding how a hormone receptor is regulated, potentially reducing postpartum hemorrhage risk.
-
Personalized Postpartum Bleeding Risk Prediction with Machine Learning and Genetic Scores
This grant aims to create a personalized tool that predicts a mother’s risk of postpartum hemorrhage using machine learning and her genetic information.
-
OPTIMUM OB-TXA: Timing, route, and dose of tranexamic acid to prevent postpartum bleeding before cord clamping
Aims to find the best time, method, and amount of tranexamic acid given before cord clamping to prevent postpartum hemorrhage in new mothers and protect babies.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.