Opening the maternal cord clamp to speed placental delivery and reduce postpartum bleeding
Official title: The Effect of Placental Cord Drainage on the Third Stage of Labor and the Amount of Postpartum Bleeding
Run by Saglik Bilimleri Universitesi Gulhane Tip Fakultesi · NCT07279545 · Data updated 2026-11-12
This test will see if opening the clamp on the mother's end of the cut umbilical cord helps the placenta come out sooner and reduces bleeding in low-risk, full-term women after a vaginal birth.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 35 Years |
| Sex | Women only |
| Enrollment | 80 (estimated) |
| Sponsor | Saglik Bilimleri Universitesi Gulhane Tip Fakultesi Academic / other |
| Locations | 1 site (Zonguldak, Zonguldak/Centre) |
| Status | Recruiting |
| Started | November 17, 2025 |
| Main results expected | June 20, 2026 |
| Study ends | July 1, 2026 |
| Registry record updated | December 12, 2025 |
| Trial ID | NCT07279545 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are low‑risk, Turkish‑speaking pregnant women at 37–41 weeks with vertex presentation planning a vaginal birth, who have no maternal or fetal complications, normal hemoglobin/hematocrit, are not on anticoagulants or smoking, and report low pain at enrollment.
✕Probably not a fit
Women with high‑risk pregnancies, a history of postpartum hemorrhage, anemia, anticoagulant use, active smoking, non‑vertex presentation, or who cannot deliver at the study hospital are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
After the baby is born and the umbilical cord is clamped and cut, the clamp on the maternal end is opened to allow blood to drain from the placenta; timing of placental delivery and blood loss are then measured. The study compares outcomes including duration of the third stage of labor, blood loss during the third stage, bleeding in the first two hours after birth, and postpartum complications. Eligible participants are low‑risk, Turkish‑speaking women at 37–41 weeks with a vertex presentation and no maternal or fetal complications; women with prior postpartum hemorrhage, anemia, anticoagulant use, smoking, or short birth intervals are excluded. Data are collected in a hospital setting at the time of delivery to capture immediate bleeding and clinical events.
Why it matters
Potential benefit: If successful, this simple maneuver could shorten the third stage of labor and reduce postpartum blood loss, lowering the risk of hemorrhage.
How similar studies have gone: Some prior studies and reviews suggest placental cord drainage can shorten the third stage and modestly reduce blood loss, but results have been mixed and it is not uniformly adopted.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * No problem speaking and understanding Turkish * Low-risk pregnant women * Vertex presentation * 37-41st weeks of gestation * There are no complications in the mother or the baby that prevent normal birth. * The VAS score for the pain felt by the pregnant woman at the time of admission to the study must be less than 3 (to show that the pregnant women were accepted into the study at a time when their pain was at its lowest and their decision-making ability was at a relatively good level) Exclusion Criteria: * History of postpartum hemorrhage * History of postpartum hemorrhage in mother or sister * Birth interval less than 2 years * Anticoagulant use during pregnancy * Smoking during pregnancy * Those with low Hb values (Hb\<11gr/dL) * Hematocrit \<30
Where it's running
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Zonguldak Maternity and Child Diseases Hospital
Zonguldak, Zonguldak/Centre, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Ferhat TÜFEKÇİ, Spc. Dr. — Zonguldak Maternity and Child Diseases Hospital
- Study coordinator: Sinem GÜLTEKİN, Phd
- Email: sinemgultekin06@gmail.com
- Phone: 05546531112
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Draining the umbilical cord after birth to lower postpartum bleeding
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.