Condition

Post Operative Analgesia clinical trials and research

• 10Clinical trials
• 2NIH research projects
• 6Countries

Newest Post Operative Analgesia clinical trials

All recruiting trials (10)

• Postoperative tizanidine addition after pelvic reconstructive surgery

  This study tests whether adding tizanidine to the usual postoperative pain plan helps adult women recover better after urogynecologic pelvic reconstructive surgery.

  Recruiting Phase 2 Hartford Hospital · Hartford, Connecticut · NCT07766837

• Combined PECS II and PIP blocks vs TPVB for post-mastectomy pain relief

  This trial tests whether a combination of PECS II and superficial PIP blocks can provide better or similar pain relief after mastectomy compared with the standard thoracic paravertebral block.

  Recruiting Dharmais National Cancer Center Hospital · Jakarta, DKI Jakarta · NCT07738770

• Low vs. standard volume EXORA block for pain control in laparoscopic gallbladder surgery

  This trial tests whether a smaller amount of local anesthetic given as a bilateral EXORA block provides pain relief after laparoscopic cholecystectomy.

  Recruiting Fayoum University Hospital · El Fayoum Qesm, Faiyum Governorate · NCT07507799

• Peripheral autonomic plus TAP blocks for pain after minimally invasive left-sided colorectal surgery

  This will try adding a peripheral autonomic block (targeting the superior hypogastric and inferior mesenteric plexuses) plus a TAP block to standard pain control in adults having elective minimally invasive left-sided colorectal surgery to see if it reduces pain and opioid use in the first 48 hours.

  Recruiting Faculdade de Ciências Médicas de Minas Gerais · Belo Horizonte, Minas Gerais · NCT07388953

• Dexmedetomidine versus dexamethasone added to ropivacaine for supraclavicular nerve block in upper‑limb surgery

  This test compares two medicines added to ropivacaine to see which gives faster onset and longer pain relief for adults having upper‑limb surgery with an ultrasound‑guided supraclavicular nerve block.

  Recruiting Phase 2/3 Sahiwal medical college sahiwal · Sāhīwāl, Punjab Province · NCT07290595

• Adding targeted posterior knee nerve blocks to the adductor canal block for pain control after total knee replacement

  This trial will test whether adding one of three different posterior knee nerve blocks to a standard adductor canal block reduces pain and opioid use for adults having a single total knee replacement.

  Recruiting Erzincan University · Erzincan, Merkez · NCT07242170

• Perioperative Lidocaine in Enhanced Recovery After Major Non-Cardiac Surgery

  This trial tests whether giving IV lidocaine during major non-cardiac surgery helps recovery and reduces opioid use in adults within an ERAS program.

  Recruiting Phase 4 Vanderbilt University Medical Center · Nashville, Tennessee · NCT07224711

• Supra- versus infra-inguinal fascia iliaca blocks for easier spinal positioning and pain relief in lower limb surgery

  This test will compare two ultrasound-guided fascia iliaca nerve blocks to see which helps adults aged 30–60 with thigh or knee fractures have less pain and easier positioning for spinal anesthesia.

  Recruiting Phase 2/3 Sahiwal medical college sahiwal · Sāhīwāl, Punjab Province · NCT07221682

• Dexamethasone to prolong spinal anesthesia for cesarean delivery

  This trial tests whether a single IV dose of dexamethasone given around an elective C-section helps spinal anesthesia and postoperative pain relief last longer than a placebo.

  Recruiting Phase 4 Rawalpindi Medical College · Rawalpindi, Punjab Province · NCT07088146

• Local anesthetic injection to reduce pain after hysterectomy

  This study tests if injecting a local anesthetic into the vaginal cuff during a hysterectomy can help reduce pain after surgery and lower the need for pain medication for patients having the procedure for non-cancerous reasons.

  Recruiting Phase 4 MediSys Health Network · Flushing, New York · NCT06719180

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Long-lasting, non-addictive implant for pain after surgery

  This project offers a one-time injectable implant that slowly releases a local anesthetic to help people recovering from oral and facial surgery have longer-lasting, non‑addictive pain relief.

  NIH research University of Kentucky · Lexington, United States · NIH-11257347

• A new implant for long-lasting pain relief without addiction

  This study is testing a new implant that can provide pain relief directly where you had surgery, helping to manage your pain for up to a week without relying on traditional painkillers, which can be addictive, especially for patients having oral facial surgery.

  NIH research University of Kentucky · Lexington, United States · NIH-11117284

Related topics

Quick answers

How many Post Operative Analgesia clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (3 trials), Pakistan (3 trials), Brazil (1 trial), Indonesia (1 trial), Egypt (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 3, Phase 2/3: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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