Supra- versus infra-inguinal fascia iliaca blocks for easier spinal positioning and pain relief in lower limb surgery
Official title: Comparison For Ease Of Spinal Positioning & Duration Of Post-Op Analgesia Between Ultrasound Guided Supra-Inguinal Fascia Iliaca Block Vs Ultrasound Guided Infra-Inguinal Fascia Iliaca Block In Patients Undergoing Thigh & Knee Surgeries
Run by Sahiwal medical college sahiwal · NCT07221682 · Data updated 2026-11-12
This test will compare two ultrasound-guided fascia iliaca nerve blocks to see which helps adults aged 30–60 with thigh or knee fractures have less pain and easier positioning for spinal anesthesia.
Quick facts
| Phase | Phase2; Phase3 |
|---|---|
| Study type | Interventional |
| Ages | 30 Years to 60 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Sahiwal medical college sahiwal Government |
| Locations | 1 site (Sāhīwāl, Punjab Province) |
| Status | Recruiting |
| Started | May 6, 2024 |
| Main results expected | October 25, 2026 |
| Study ends | January 1, 2027 |
| Registry record updated | January 29, 2026 |
| Trial ID | NCT07221682 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 30–60 with ASA class I–III undergoing thigh or knee surgery who have painful fractures, can give informed consent, and have no contraindications to spinal anesthesia or peripheral nerve blocks.
✕Probably not a fit
Patients with coagulopathy, significant cognitive impairment, polytrauma, allergy to the study drugs, no pain when sitting without support, or other contraindications to spinal or peripheral nerve blocks, as well as those outside the age range, are unlikely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a randomized, controlled, double-blind (observer and patient-blinded) trial enrolling 60 adults undergoing thigh or knee surgery who meet inclusion criteria. Patients are randomized to receive either an ultrasound-guided supra-inguinal or infra-inguinal fascia iliaca block with 30 ml of 0.125% bupivacaine in the preoperative area. Blocks are performed under ultrasound guidance, and outcomes include ease of spinal positioning using the EOSP score, numeric pain rating scores at rest and on movement, hemodynamic events, and post-operative analgesia and patient satisfaction. Allocation uses computer-generated random numbers and sequentially numbered opaque envelopes to maintain concealment.
Why it matters
Potential benefit: If successful, the preferred block technique could reduce pain during spinal positioning, improve post-operative pain control, and lower opioid requirements.
How similar studies have gone: Prior studies indicate fascia iliaca blocks can reduce pain and aid positioning, but direct randomized comparisons of supra- versus infra-inguinal approaches are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Both Genders (Male /Female). 2. Age between 30 years to 60 years. 3. ASA Class I, II, III. Exclusion Criteria: 1. Patient refusal 2. Other distracting painful pathology 3. Any contraindication to Spinal Anesthesia or peripheral nerve blocks 4. Coagulopathic disorders 5. Patients with significant cognitive impairment 6. Patients with no pain while sitting by themselves without any support 7. H/O polytrauma involving other limbs 8. H/O allergy to the drugs used in study
Where it's running
-
Sahiwal Medical College Sahwal
Sāhīwāl, Punjab Province, Pakistan Recruiting
Study contacts
- Study coordinator: Dr Humaira Shahzadi, MBBS
- Email: humairaali2323@gmail.com
- Phone: 00923044128425
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.