Low vs. standard volume EXORA block for pain control in laparoscopic gallbladder surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, randomized, double-blinded study compares two bilateral EXORA block volumes (15 mL vs 25 mL per side) using 0.25% bupivacaine in patients undergoing elective laparoscopic cholecystectomy. Participants are allocated to one of two groups before anesthesia, with blinding maintained for patients, surgical team, anesthesiologists, and data collectors. The primary aim is to evaluate analgesic efficacy while monitoring safety and intraoperative/postoperative management within a standardized anesthesia protocol. Block performance is ultrasound-guided and performed by a designated anesthesiologist not involved in postoperative care. Outcomes will include postoperative analgesia requirements and pain scores within the first 24 hours.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* American Society of Anesthesiologists (ASA) physical status I or II.
* Scheduled for elective laparoscopic cholecystectomy under general anesthesia.

Exclusion Criteria:

* • Patient refusal to participate.

  * Obese patients with a body mass index of more than 35 kg/m2.
  * Known cognitive impairment or use of psychiatric drugs
  * Known allergy to local anesthetics
  * Infection at the needle insertion site.
  * Coagulopathy, or bleeding disorders.
  * Pregnancy
  * History of chronic pain or chronic opioid use.
  * Previous major upper abdominal surgery (which alters the fascial planes and anatomy).

Criteria for Withdrawal from Study Analysis (Drop-outs):

* Conversion to open cholecystectomy during surgery.
* Failed EXORA block

Where it's running

• Fayoum University hospital
  El Fayoum Qesm, Faiyum Governorate, Egypt Recruiting

Study contacts

• Principal investigator: Mohamed A Hamed,, MD — Faculty of medicine, Fayoum university
• Study coordinator: Mohammed R Gomaa, Bch
• Email: mr147@fayoum.edu.eg
• Phone: 1097830069

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.