Condition

Physiological Stress clinical trials and research

• 13Clinical trials
• 9NIH research projects
• 3Countries

Newest Physiological Stress clinical trials

All recruiting trials (13)

• Do electric fans help kids stay cooler during heat waves

  This study tests whether using electric fans at midday helps children and young adults stay cooler and feel better when exposed to prolonged indoor heat.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07864103

• Lower Body Negative Pressure to See if Noninvasive Monitors Are Accurate

  This study tests whether noninvasive physiological monitors accurately track body responses while the body experiences controlled lower body negative pressure.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07840144

• How kids and young adults regulate body temperature during exercise at different ambient temperatures

  This study tests how children aged 9-16 and young adults aged 20-25 handle heat during exercise at four different room temperatures.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07781605

• Heat and hypoxia: how simulated altitude affects body temperature and strain

  This study tests how heat exposure with and without simulated altitude affects core temperature and physiological strain in healthy, physically active adult men.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07664462

• Consecutive Occupational Heat Exposure With and Without Overnight Cooling

  This study tests how overnight cooling versus no cooling affects workers’ body temperature and heat stress during repeated heat exposure shifts.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07656519

• Feel Free Classic Tonic to reduce stress in healthy adults

  This will test whether the Feel Free Classic Tonic (containing kava and kratom) can reduce how stressed healthy adults aged 21–55 feel and change physiological stress markers.

  Recruiting Botanic Tonics, LLC · Guelph, Ontario · NCT07469527

• Daily cranberry juice to boost stress resilience during multitasking

  This will test whether 70 days of daily cranberry juice helps healthy adults aged 30–55 stay calmer and perform better on thinking and motor tasks when multitasking.

  Recruiting University of Florida · Gainesville, Florida · NCT07453537

• How indoor heat affects people with schizophrenia

  This study will test whether simulated indoor overheating causes more physiological stress and worsened cognitive symptoms in people with schizophrenia compared with people without schizophrenia.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07383324

• Keeping indoor temperature at 26 °C to reduce heat strain in healthy young adults

  This will test whether keeping indoor temperatures at 26 °C protects healthy, habitually active young adults from heat strain and cognitive changes.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07267598

• How indoor overheating affects children's bodies and thinking

  This project will test whether keeping indoor air at or below 26 °C (about 45% relative humidity) reduces heat-related physical strain and short-term cognitive changes in children.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07261202

• Is a 26°C indoor temperature safe for older adults when wearing everyday clothes or doing normal activities?

  This trial will test whether keeping indoor temperatures at or below 26°C protects older adults from heat strain when they wear everyday clothing or do normal daily activities.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07189507

• How indoor humidity affects older adults' bodies during a heat wave

  This trial will test whether higher indoor humidity makes heat harder on older adults, including some with controlled high blood pressure or long-standing type 2 diabetes.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT06842953

• Understanding health trends in Puerto Rico

  This study is trying to understand health trends in Puerto Rico by looking at diet, mental health, and heart health in adults aged 30-75 over time.

  Recruiting Harvard School of Public Health (HSPH) · San Juan · NCT03794531

NIH-funded research (9)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Molecular factors that control stress granules in nerve cells

  This funding supports research to understand how stress granules form and behave in nerve cells after injury, to see how they affect healing and growth.

  NIH research Rutgers the State Univ of Nj Newark · Newark, United States · NIH-11428320

• Physiological stress and behavior shaping Latino children's learning and health

  This grant explores how stress regulation and behavior relate to how Latino children adapt and learn as they grow.

  NIH research University of Georgia · Athens, United States · NIH-11413820

• How where teens live and go about life affects stress and health

  This grant studies how everyday spaces and feelings of safety influence stress hormones and health in adolescents.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11381598

• How joints respond to everyday loading with age, sex, and osteoarthritis

  This project uses PET‑MRI scans taken before and after normal joint loading to measure bone and cartilage responses in older adults and people with osteoarthritis.

  NIH research Stanford University · Stanford, United States · NIH-11300171

• How family culture and stress affect Latin American children's behavior and school readiness

  This project looks at whether parents' stress responses and culturally rooted parenting help Latin American children (ages 1–11) with self-control, behavior, and early school skills.

  NIH research University of Georgia · Athens, United States · NIH-11145106

• How neighborhood places and safety shape teen stress and health

  This project looks at how teens' everyday places and feelings of safety relate to their stress levels, substance use, and mental health using surveys, location information, and biological stress tests.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11132987

• How early life lead exposure and stress affect heart and metabolic health over time

  This study is looking at how being exposed to lead and experiencing stress when you're young can affect your heart and overall health as you get older, and it’s for anyone interested in understanding how these early life experiences might impact their well-being later in life.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11051938

• How joints respond to stress as we age and in osteoarthritis

  This study is looking at how osteoarthritis affects your joints and how they respond to everyday activities, especially as you get older, using special imaging techniques to find early signs of the condition before serious damage happens.

  NIH research Stanford University · Stanford, United States · NIH-11045792

• Understanding how stress affects behavior and learning in Latinx children

  This study looks at how stress affects learning and behavior in Latinx children and how their parents can help them cope better, with a focus on cultural support to improve their school readiness and overall development.

  NIH research University of Georgia · Athens, United States · NIH-10896169

Related topics

Quick answers

How many Physiological Stress clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in Canada (10 trials), United States (2 trials), Puerto Rico (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →