How early life lead exposure and stress affect heart and metabolic health over time
Official title: The joint effects of early life lead exposure, and psychosocial co-exposures, on physiological stress and cardiometabolic health across the life course
Funded at University of Michigan at Ann Arbor · NIH-11051938 · Data updated 2026-11-12
This study is looking at how being exposed to lead and experiencing stress when you're young can affect your heart and overall health as you get older, and it’s for anyone interested in understanding how these early life experiences might impact their well-being later in life.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | March 20, 2025 |
| Project end | February 28, 2027 |
| Funding year | 2025 |
| Award (this year) | $107,493 |
| NIH project number | 1K99ES036294-01A1 |
| Project ID | NIH-11051938 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include children and adolescents aged 0-20 who have experienced lead exposure or psychosocial stress.
✕Less likely to help
Patients who have not been exposed to lead or psychosocial stressors may not benefit from this research.
What this research studies
This research investigates the combined effects of lead exposure and psychosocial stressors during early life on heart and metabolic health as individuals grow older. It aims to understand how these factors interact to influence physiological stress responses, potentially leading to increased health risks later in life. By examining both negative and positive exposures, the study seeks to identify risk and protective factors that could inform future health interventions. Participants may undergo assessments to evaluate their exposure history and health outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing cardiometabolic diseases in individuals exposed to lead and psychosocial stressors during childhood.
How similar studies have gone: While the individual effects of lead exposure and psychosocial stress have been studied, this research is novel in examining their combined impact on health outcomes.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Halabicky, Olivia Maryfrances — University of Michigan at Ann Arbor
- Study coordinator: Halabicky, Olivia Maryfrances
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.