Molecular factors that control stress granules in nerve cells
Official title: Molecular Determinants of Physiological Stress Granule Homeostasis and Function.
Funded at Rutgers the State Univ of Nj Newark · NIH-11428320 · Data updated 2026-11-12
This funding supports research to understand how stress granules form and behave in nerve cells after injury, to see how they affect healing and growth.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers the State Univ of Nj Newark NIH-funded |
| Lab location | 1 site (Newark, United States) |
| Project start | July 15, 2026 |
| Project end | April 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $431,750 |
| NIH project number | 1R35GM165886-01 |
| Project ID | NIH-11428320 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are patients with nervous system injuries or diseases where nerve healing and regeneration are part of care, or who could contribute samples for related research.
✕Less likely to help
Patients without nervous system injury or disease may not directly benefit from this basic science study.
What this research studies
Researchers will study stress granules, tiny structures in cells that manage RNA during stress, using nerve injury in animal or cellular models. They will identify which proteins and RNAs make up axonal stress granules and how they change as neurons grow and repair. The study aims to uncover molecular steps that could be targeted to improve nerve regeneration and reduce disease-related cell damage. The project builds a bridge between basic cell biology and potential therapies for nervous system injuries and related conditions.
Why it matters
Potential benefit: If successful, this work could point to new approaches to promote nerve repair and reduce degeneration in nervous system diseases.
How similar studies have gone: Prior studies have shown that stress granule biology relates to disease; this project extends those findings to axons and neural injury, with promising potential but still early.
Where this research is happening
-
Rutgers the State Univ of Nj Newark
Newark, United States Active
Researchers
- Principal investigator: Sahoo, Pabitra K. — Rutgers the State Univ of Nj Newark
- Study coordinator: Sahoo, Pabitra K.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.