How neighborhood places and safety shape teen stress and health

Activity Space Exposures, Safety and Physiological Stress, and their Consequences for Adolescent Health

NIH-funded research Ohio State University · NIH-11132987

This project looks at how teens' everyday places and feelings of safety relate to their stress levels, substance use, and mental health using surveys, location information, and biological stress tests.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project IDNIH-11132987 on NIH RePORTER

What this research studies

You would join a group of about 700 adolescents (and their caregivers) in the Columbus, OH area who complete surveys about routines, safety, and health. The team will combine your reported routine locations with neighborhood data on violence and social belonging, and collect biological stress markers like cortisol and inflammation measures. A smaller subsample will take part in an intensive six-month follow-up with frequent check-ins to capture real-time experiences, locations, and stress responses. The study aims to link where you go and how safe you feel to changes in stress, substance use, and mental health over time.

Who could benefit from this research

Good fit: Ideal participants are adolescents about 12–20 years old who live in the Columbus, OH metropolitan area and are willing to complete surveys, share routine location information, and provide biological samples, with a caregiver available to participate.

Not a fit: People outside the age range or living outside the Columbus area, or those unwilling to share location or biological data, would not be eligible and would not gain direct benefits from participation.

Why it matters

Potential benefit: If successful, the work could point to neighborhood- or school-focused changes that reduce teen stress and lower risks for substance use and mental health problems.

How similar studies have performed: Prior research links neighborhood conditions to adolescent stress, but combining detailed activity-space mapping with real-time biological stress measures and longitudinal follow-up is relatively new.

Where this research is happening

Columbus, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.