Clinical trial Recruiting at 1 site Interventional Ages 9 to 25

How kids and young adults regulate body temperature during exercise at different ambient temperatures

Official title: Ambient Temperature and Thermoregulation During Moderate-Intensity Exercise in Children and Youth

Run by University of Ottawa · NCT07781605 · Data updated 2026-11-12

This study tests how children aged 9-16 and young adults aged 20-25 handle heat during exercise at four different room temperatures.

Quick facts

Study typeInterventional
Ages9 Years to 25 Years
SexAll
Enrollment12 (estimated)
SponsorUniversity of Ottawa
Academic / other
Locations1 site (Ottawa, Ontario)
StatusRecruiting
StartedJuly 19, 2026
Main results expectedApril 30, 2027
Study endsJune 30, 2027
Registry record updatedNovember 10, 2026
Trial IDNCT07781605 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Healthy boys and girls aged 9-16 years and healthy men and women aged 20-25 years who are regularly active and able to communicate in English or French.

Probably not a fit

Individuals with acute illness, chronic conditions affecting thermoregulation or cardiovascular function, or a history of heat-related illnesses may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Healthy participants in two age groups perform short bouts of moderate-intensity exercise in a temperature-controlled chamber at 22°C, 26°C, 31°C, and 36°C. Each visit includes four 15-minute exercise periods with rests in between, allowing precise measurement of heat loss and thermoregulation. Researchers compare responses between youths and young adults to see how ambient temperature affects heat exchange and tolerance during physical activity. The study uses a whole-body air calorimeter to quantify body heat loss during exercise.

Why it matters

Potential benefit: If successful, findings could improve guidelines for safe exercise in varying temperatures for children and adolescents.

How similar studies have gone: Prior research in thermoregulation supports that ambient temperature influences heat exchange during exercise, though data in children are limited and this study extends that work.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Healthy male or female.
* Aged 9-16 years or 20-25 years.
* Habitually active, defined as participating in regular physical activity at least 3 times per week for at least 20 minutes per session over the previous 6 months.
* Able to understand and communicate in English or French.
* For participants younger than 18 years, written parental or guardian consent and participant assent are required.

Exclusion Criteria:

* Acute illness at the time of testing (e.g., cold, flu, or infection).
* History of a chronic medical condition that may affect thermoregulation, cardiovascular function, or exercise capacity (e.g., cardiovascular disease, metabolic disorders, respiratory disease including asthma requiring regular medication, or neurological disorders).
* Use of medications known to affect thermoregulation, hydration status, or cardiovascular responses.
* History of heat-related illness (e.g., heat exhaustion or heat stroke).
* Digestive abnormalities or gastrointestinal conditions that may contraindicate ingestion of a telemetry pill.
* Any condition that, in the opinion of the investigators, would compromise participant safety or the integrity of the data.

Where it's running

  • University of Ottawa
    Ottawa, Ontario, Canada
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.