How joints respond to stress as we age and in osteoarthritis
Imaging of Joint Response to Physiological Stress with Age, Sex and in Osteoarthritis
This study is looking at how osteoarthritis affects your joints and how they respond to everyday activities, especially as you get older, using special imaging techniques to find early signs of the condition before serious damage happens.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11045792 on NIH RePORTER |
What this research studies
This research investigates how osteoarthritis (OA) affects joint function and tissue response to everyday physical stress, particularly focusing on the role of age. Using advanced imaging techniques like PET-MRI, the study aims to identify early markers of OA by evaluating changes in bone metabolism and joint loading. The goal is to develop a novel imaging 'stress test' that can detect OA at an early stage, potentially before irreversible damage occurs. This approach seeks to improve our understanding of how aging influences joint health and response to physical activity.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults experiencing joint pain or those at risk for developing osteoarthritis.
Not a fit: Patients with advanced osteoarthritis or those who do not experience joint pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and better management of osteoarthritis, improving quality of life for patients.
How similar studies have performed: Other research has shown promise in using advanced imaging techniques to assess joint health, suggesting that this approach could yield valuable insights.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Kogan, Feliks — Stanford University
- Study coordinator: Kogan, Feliks
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.