Clinical trial Recruiting at 1 site Interventional Ages 50 to 75 Men only

Consecutive Occupational Heat Exposure With and Without Overnight Cooling

Official title: Physiological Responses to Consecutive Days of Occupational Heat Exposure With and Without Overnight Access to Cooling

Run by University of Ottawa · NCT07656519 · Data updated 2026-11-12

This study tests how overnight cooling versus no cooling affects workers’ body temperature and heat stress during repeated heat exposure shifts.

Quick facts

Study typeInterventional
Ages50 Years to 75 Years
SexMen only
Enrollment10 (estimated)
SponsorUniversity of Ottawa
Academic / other
Locations1 site (Ottawa, Ontario)
StatusRecruiting
StartedJune 24, 2026
Main results expectedJune 30, 2027
Study endsAugust 31, 2027
Registry record updatedOctober 5, 2026
Trial IDNCT07656519 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are physically active, non-smoking men without regular exposure to hot work environments who can consent and speak English or French.

Probably not a fit

Individuals who are regularly exposed to hot work environments or have certain medical conditions or uncontrolled hypertension may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study examines whether recovering in an overheated indoor setting versus a recommended cool indoor environment changes physiological heat strain after consecutive work shifts in hot conditions. Participants undergo simulated occupational heat exposure under two recovery conditions: with indoor cooling at recommended temperatures and with no cooling in an overheated space. The trial focuses on core temperature, physiological responses, and tolerance to repeated heat exposure, aiming to inform guidelines for recovery environments between shifts. It targets healthy, physically active men who are English or French speakers and not regularly exposed to hot work environments. The study is conducted at the University of Ottawa under the lead sponsorship of the same institution.

Why it matters

Potential benefit: If successful, the findings could guide safer recovery practices between hot-work days and reduce heat-related illness risk for workers.

How similar studies have gone: Previous research on heat exposure and recovery conditions supports that environmental factors can influence thermoregulation, though this exact recovery-setting comparison is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Are male.
* Do not smoke or have been smoke free for at least 5 years.
* English or French speaking.
* Ability to provide informed consent.
* Are physically active (engage in exercise at least 2 times per week for ≥30 minutes)

Exclusion Criteria:

* Are regularly exposed to hot environments (e.g., occupational heat exposure)
* Experience claustrophobia or discomfort in enclosed environments
* Episode(s) of severe hypoglycemia (requiring the assistance of another person) within the previous year, or inability to sense hypoglycemia (hypoglycemia unawareness).
* Serious complications related to diabetes (gastroparesis, renal disease, uncontrolled hypertension, severe autonomic neuropathy).
* Uncontrolled hypertension - BP \>150 mmHg systolic or \>95 mmHg diastolic in a sitting position.
* Restrictions in physical activity due to disease (e.g. intermittent claudication, renal impairment, active proliferative retinopathy, unstable cardiac or pulmonary disease, disabling stroke, severe arthritis, etc.).
* Use of or changes in medication judged by the patient or investigators to make participation in this study inadvisable.
* Cardiac abnormalities identified during screening

Where it's running

  • University of Ottawa
    Ottawa, Ontario, Canada
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.