NIH-funded research R01 grant

How where teens live and go about life affects stress and health

Official title: Activity Space Exposures, Safety and Physiological Stress, and their Consequences for Adolescent Health

Funded at Ohio State University · NIH-11381598 · Data updated 2026-11-12

This grant studies how everyday spaces and feelings of safety influence stress hormones and health in adolescents.

More Physiological Stress research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startSeptember 15, 2023
Project endJune 30, 2028
Funding year2026
Award (this year)$653,962
NIH project number5R01HD113259-04
Project IDNIH-11381598 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are adolescents aged roughly 12–20 (with emphasis on early to late adolescence) residing in the Columbus, OH metro area and their caregivers.

Less likely to help

Adolescents outside the Columbus area or not willing to participate in longitudinal data collection may not directly benefit.

What this research studies

Researchers at Ohio State University will track teens in Columbus to see how their daily activity spaces—where they go, who they’re with, levels of neighborhood violence, and feelings of belonging—shape real-time stress and later health outcomes. The study uses surveys, contextual data, and biological markers like cortisol and inflammation to understand stress in adolescence. A first phase creates a broad picture in about 700 youths and caregivers, combining self-reported activity locations with community data, then a six-month intensive follow-up in a subset to look at dynamic patterns. The goal is to link everyday environments to mental health and substance use, informing interventions to promote safer, healthier adolescent development.

Why it matters

Potential benefit: If successful, findings could inform programs and policies to improve adolescent environments and reduce stress-related health risks.

How similar studies have gone: Previous work has linked neighborhood factors and stress to health, but this project adds real-time exposure measures and a longitudinal design to deepen understanding.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: Browning, Christopher R — Ohio State University
  • Study coordinator: Browning, Christopher R

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.