Condition

Heat Stress clinical trials and research

• 17Clinical trials
• 8NIH research projects
• 2New in 30 days
• 6Countries

Newest Heat Stress clinical trials

All recruiting trials (17)

• Heat and Mood in Young Adults with Depression

  This study tests whether hot indoor environments affect mood in young adults with depression and whether daytime heat harms mood more than nighttime heat.

  Recruiting Hartford Hospital · Orange, Connecticut · NCT07903896

• Testing ways to keep kids cooler in school in climate-vulnerable districts of Bangladesh

  We’re testing whether combining heat education with simple school upgrades can reduce heat-related illnesses and improve learning for 7–14 year-olds in two climate-vulnerable districts of Bangladesh.

  Recruiting at 2 sites BRAC University · Gaibandha, Rangpur Division and 1 other locations · NCT07877935

• Do electric fans help kids stay cooler during heat waves

  This study tests whether using electric fans at midday helps children and young adults stay cooler and feel better when exposed to prolonged indoor heat.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07864103

• How kids and young adults regulate body temperature during exercise at different ambient temperatures

  This study tests how children aged 9-16 and young adults aged 20-25 handle heat during exercise at four different room temperatures.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07781605

• Heat and hypoxia: how simulated altitude affects body temperature and strain

  This study tests how heat exposure with and without simulated altitude affects core temperature and physiological strain in healthy, physically active adult men.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07664462

• Consecutive Occupational Heat Exposure With and Without Overnight Cooling

  This study tests how overnight cooling versus no cooling affects workers’ body temperature and heat stress during repeated heat exposure shifts.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07656519

• Hot baths before or after exercise to speed muscle recovery and boost HSP70

  This trial will test whether taking a hot bath before or after intense muscle-lengthening exercise helps speed recovery and increase protective HSP70 levels in healthy athletic men.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07559344

• Psycho-physiological profiling of people with low versus high heat resilience

  This project will test whether controlled heat and UV exposures plus physiological and psychological measurements can identify healthy adults who are more or less resilient to heat.

  Recruiting at 2 sites University of Thessaly · Copenhagen and 1 other locations · NCT07510061

• How indoor heat affects people with schizophrenia

  This study will test whether simulated indoor overheating causes more physiological stress and worsened cognitive symptoms in people with schizophrenia compared with people without schizophrenia.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07383324

• Keeping indoor temperature at 26 °C to reduce heat strain in healthy young adults

  This will test whether keeping indoor temperatures at 26 °C protects healthy, habitually active young adults from heat strain and cognitive changes.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07267598

• How indoor overheating affects children's bodies and thinking

  This project will test whether keeping indoor air at or below 26 °C (about 45% relative humidity) reduces heat-related physical strain and short-term cognitive changes in children.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07261202

• Is a 26°C indoor temperature safe for older adults when wearing everyday clothes or doing normal activities?

  This trial will test whether keeping indoor temperatures at or below 26°C protects older adults from heat strain when they wear everyday clothing or do normal daily activities.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07189507

• Wearing a hijab and whole-body heat loss during exercise in hot, dry conditions

  This study will test whether wearing a hijab changes how healthy young women lose body heat during moderate exercise in hot, dry conditions.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07174180

• Air conditioning and energy support for older adults in Boston

  This project will test whether giving window air conditioners and a later electricity subsidy to older adults without home cooling improves heat-related health, comfort, and healthcare use.

  Recruiting Harvard School of Public Health (HSPH) · Boston, Massachusetts · NCT06982339

• Cooling homes to reduce heat stress for low-income residents in Dhaka, Bangladesh

  This project will try installing cooling infrastructure and equipment in low-income Dhaka homes to see if it lowers indoor heat exposure and improves heart rate, heart rate variability, and sleep.

  Recruiting University of California, Berkeley · Dhaka, Dhaka Division · NCT06979258

• How indoor humidity affects older adults' bodies during a heat wave

  This trial will test whether higher indoor humidity makes heat harder on older adults, including some with controlled high blood pressure or long-standing type 2 diabetes.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT06842953

• Effects of beta blockers on body temperature in older adults during heat exposure

  This study is testing how two common heart medications, propranolol and metoprolol, affect body temperature in older adults when they are exposed to extreme heat.

  Recruiting Phase 4 University of Texas Southwestern Medical Center · Dallas, Texas · NCT06582680

NIH-funded research (8)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Keeping low-income homes in Dhaka cooler and safer

  This project will try low-cost, culturally acceptable ways to cool indoor spaces for adults living in Dhaka's informal settlements to reduce heat stress and heart strain.

  NIH research University of California Berkeley · Berkeley, United States · NIH-11512532

• Reducing harmful indoor heat in low-income homes in Dhaka

  This project tests low-cost, culturally acceptable cooling changes in homes to lower heat stress and heart strain for adults living in informal settlements in Dhaka, Bangladesh.

  NIH research University of California Berkeley · Berkeley, United States · NIH-11321199

• Children's heart health and the effects of heat and wildfire smoke

  This work looks at how heat waves and wildfire smoke during pregnancy and childhood may affect children's heart health.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11262924

• Heat stress and firefighter motor performance

  This project tests how rapid heat buildup from PPE affects how firefighters walk and perform fine motor tasks.

  NIH research Louisiana State Univ Hsc Shreveport · Shreveport, United States · NIH-11214656

• Investigating how heat stress affects kidney health and the role of niacinamide in prevention.

  This study is looking at how working in the heat affects kidney health, especially for sugarcane workers who might be at risk for kidney problems, and it will also test if a vitamin called niacinamide can help protect their kidneys from damage.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11160757

• Investigating heat stress and health risks in vulnerable populations in Bangladesh

  This study is looking at how heat affects people living in low-income areas of Bangladesh, especially those without air conditioning, and it will test affordable ways to keep homes cooler to help protect their health.

  NIH research University of California Berkeley · Berkeley, United States · NIH-11064893

• How the brain regulates body temperature during extreme heat

  This study is looking at how our brains help us cool down when we get too hot, focusing on certain brain cells that kick in during high temperatures, and it’s designed for anyone interested in how our bodies handle heat stress.

  NIH research Scintillon Institute for Photobiology · San Diego, United States · NIH-11056686

• Understanding how HSP70 helps cells cope with heat stress

  This study is looking at how a special protein called HSP70 helps our cells handle stress, especially when it gets too hot, and it could lead to new treatments for diseases like cancer and heart problems.

  NIH research University of Mississippi · University, United States · NIH-11043641

Related topics

Quick answers

How many Heat Stress clinical trials are recruiting right now?

17, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in Canada (10 trials), United States (3 trials), Bangladesh (2 trials), France (1 trial), Denmark (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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