Condition

Migraine Disorders clinical trials and research

• 16Clinical trials
• 9Countries

Newest Migraine Disorders clinical trials

All recruiting trials (16)

• HEADS Registry: Headache, Ear, Auditory, Dizziness, and Sinus</n> Registry

  This registry tests whether collecting online symptom reports from adults in the U.S. with sinus, vestibular, ear, or headache symptoms can help improve diagnosis and treatment.

  Recruiting Association of Migraine Disorders · North Kingstown, Rhode Island · NCT07754266

• MMA Embolization for Migraine: Patient-Reported Outcomes from a Single Site

  This registry tests whether adults with migraine who have or plan to have middle meningeal artery embolization notice changes in headaches and quality of life over time.

  Recruiting Cortex Neurovascular · Tacoma, Washington · NCT07652034

• Greater Occipital Nerve Block for Migraine with Medication Overuse Headache

  This study will test whether a nerve block using lidocaine and methylprednisolone can help people with migraine who overuse medications to reduce withdrawal headaches during detoxification.

  Recruiting at 2 sites Mahidol University · Bangkok, Bangkok and 2 other locations · NCT07568496

• Closing a PFO to improve glymphatic function and migraine symptoms

  This study will see if closing a patent foramen ovale (PFO) improves glymphatic system function and reduces migraine attacks in adults with PFO and migraine.

  Recruiting at 2 sites First Affiliated Hospital Xi'an Jiaotong University · Luoyang, Henan and 1 other locations · NCT07170176

• Italian Migraine Registry (I-GRAINE-NEW)

  This registry will collect past and future clinical and healthcare data from adults with episodic or chronic migraine who come to specialized headache centers in Italy to better understand how the condition evolves and is treated.

  Recruiting IRCCS San Raffaele Roma · Roma, Roma · NCT07163416

• Topical cannabidiol (Canvert-M) for migraine attacks

  This will test whether applying Canvert-M, a topical roll-on with cannabidiol and essential oils, can reduce pain during migraine attacks in adults aged 18–55.

  Recruiting Phase 4 Alasht Pharmed · Tehran · NCT07093138

• Using closed-loop rTMS to prevent migraines

  This study is testing if a new type of brain stimulation can help people who get frequent migraines feel better and have fewer headaches.

  Recruiting Brightmind.AI · Vienna, State of Vienna · NCT06735768

• Auricular neuromodulation for episodic migraine

  This study will try a small electrical stimulation of the ear (auricular neuromodulation) to see if it reduces migraine days in adults 18–60 with moderate-to-severe episodic migraine who have not responded to at least two preventive medications.

  Recruiting at 3 sites Hôpital Européen Marseille · Marseille and 2 other locations · NCT06623188

• Immune signals and regulatory T cells in migraine

  This research will test whether blood immune markers and regulatory T cells are linked to migraine in women ages 18–50 who have migraine or certain autoimmune/inflammatory conditions.

  Recruiting University Hospital, Clermont-Ferrand · Clermont-Ferrand, AURA · NCT06426316

• Comparing telehealth cognitive behavioral therapy for youth with migraines

  This study is testing whether online therapy for kids and teens with migraines works better when combined with medication or on its own.

  Recruiting at 15 sites Children's Hospital Medical Center, Cincinnati · Birmingham, Alabama and 14 other locations · NCT05889624

• Transcranial Direct Current Stimulation for Long COVID with Headaches and Chronic Pain

  This study tests whether applying mild brain stimulation (tDCS) can help people with long COVID who have headaches, migraines, and ongoing pain.

  Recruiting at 2 sites Fundación Universidad Católica de Valencia San Vicente Mártir · Paiporta, Valencia and 1 other locations · NCT05780450

• Assessing the effectiveness of eptinezumab for migraine treatment in real-world settings

  This study is testing how well eptinezumab, an IV treatment for migraines, works in real life for people who have frequent migraines and haven't had success with other treatments.

  Recruiting IRCCS San Raffaele Roma · Roma, RM · NCT05570149

• Evaluating a lifestyle intervention for chronic migraine management

  This study is testing a new lifestyle program to see if it can help people with chronic migraines feel better compared to a control group.

  Recruiting Mayo Clinic · Phoenix, Arizona · NCT05415020

• Survey on long-term use of AJOVY for migraine treatment

  This study is looking to see how safe AJOVY is for people using it to treat migraines over a long time, especially regarding heart-related issues.

  Recruiting Otsuka Pharmaceutical Co., Ltd. · Osaka · NCT05342493

• Using Qudexy XR to prevent migraines in children aged 6 to 11

  This study is testing if Qudexy XR can help prevent migraines in children aged 6 to 11 who have a history of headaches.

  Recruiting at 6 sites Phase 4 Upsher-Smith Laboratories · Birmingham, Alabama and 14 other locations · NCT04748601

• Using Idebenone to prevent migraines

  This study is testing if a new compound called idebenone can help prevent migraines in adults by seeing if it reduces the number of migraine attacks compared to a placebo.

  Recruiting Phase 3 Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang · NCT04151472

Related topics

Quick answers

How many Migraine Disorders clinical trials are recruiting right now?

16, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (5 trials), China (2 trials), France (2 trials), Italy (2 trials), Iran (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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