Clinical trial Recruiting at 1 site Observational Ages 18 to 64

MMA Embolization for Migraine: Patient-Reported Outcomes from a Single Site

Official title: Enduring Migraine Benefit From Responsive Artery Coil Embolization - Observational (EMBRACE-OBS): A Single-Site Registry of Patient-Reported Outcomes Following Routine Clinical Care for Migraine

Run by Cortex Neurovascular · NCT07652034 · Data updated 2026-11-12

This registry tests whether adults with migraine who have or plan to have middle meningeal artery embolization notice changes in headaches and quality of life over time.

Quick facts

Study typeObservational
Ages18 Years to 64 Years
SexAll
Enrollment50 (estimated)
SponsorCortex Neurovascular
Industry-sponsored
Locations1 site (Tacoma, Washington)
StatusRecruiting
StartedSeptember 1, 2026
Main results expectedJune 1, 2028
Study endsJune 1, 2028
Registry record updatedSeptember 23, 2026
Trial IDNCT07652034 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18 to 64 with a migraine diagnosis who have undergone or plan MMA embolization as part of routine care and can consent in English.

Probably not a fit

Patients who do not undergo MMA embolization or who have incomplete data may not contribute to outcome descriptions.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

EMBRACE-OBS is a single-site registry that uses data already collected in routine care to describe how headache frequency, headache severity, and migraine-related quality of life change after MMA embolization. It does not change how patients are treated or followed. The study also documents medication use and any adverse events to understand the real-world safety and impact of the procedure. Follow-up relies on standard clinical visits and patient-reported measures such as headache diaries and validated questionnaires.

Why it matters

Potential benefit: If successful, the registry could clarify real-world outcomes and safety of MMA embolization for migraine, informing patients and clinicians.

How similar studies have gone: Other observational studies in similar real-world settings have provided useful insights into outcomes after MMA embolization for migraine, supporting the value of this registry.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18 to 64 years
* Diagnosis of migraine
* Have undergone or plan to undergo middle meningeal artery (MMA) embolization as part of routine clinical care, independent of study participation
* Able and willing to provide informed consent
* Able to read and understand English sufficiently to complete informed consent and patient-reported outcome assessments

Exclusion Criteria:

* Age under 18 years
* Pregnancy at the time of enrollment
* Inability to provide informed consent
* Inability to read and understand English sufficiently to complete informed consent and patient-reported outcome assessments
* Insufficient clinical or patient-reported outcome data for the planned analyses

Where it's running

  • Cortex Neurovascular / TRA Union
    Tacoma, Washington, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.