Assessing the effectiveness of eptinezumab for migraine treatment in real-world settings

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates the effectiveness, safety, and tolerability of eptinezumab, an intravenous treatment for migraine, in a real-life population. It targets patients with high frequency episodic migraine or chronic migraine, assessing outcomes in those who have previously failed other preventive treatments. The study involves administering eptinezumab at doses of 100 mg or 300 mg quarterly, with data collected from multiple headache centers in Italy to provide insights into its real-world application.

Why it matters

Who can join: the full rules

KEY INCLUSION CRITERIA

1. Age between 18 and 75 years;
2. Males and females;
3. Willingness to sign the informed consent;
4. High frequency episodic migraine, at least 8 days per month of disabling migraine in the past 3 months;
5. Chronic migraine, according to the ICHD-III criteria;

KEY EXCLUSION CRITERIA

1. Other headaches different than migraine;
2. Known intolerance to eptinezumab or eccipients;
3. Current treatment with other mAbs;
4. Vascular disease or Raynaud.

Where it's running

• IRCCS San Raffaele Roma
  Roma, Rm, Italy Recruiting

Study contacts

• Study coordinator: Piero Barbanti, MD, PhD
• Email: piero.barbanti@sanraffaele.it
• Phone: +393357071457

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Italian Migraine Registry (I-GRAINE-NEW)

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.