Condition

Hypertension (HTN) clinical trials and research

• 24Clinical trials
• 1New in 30 days
• 14Countries

Newest Hypertension (HTN) clinical trials

All recruiting trials (24)

• Guiding Optimal Blood Pressure in Peritoneal Dialysis

  This pilot tests whether aiming for a lower systolic blood pressure target (<120 mmHg) is feasible and practical for adults with end-stage kidney disease on peritoneal dialysis, compared to a <140 mmHg target.

  Recruiting at 2 sites University of California, San Francisco · San Francisco, California and 2 other locations · NCT07910773

• New virtual care pathway for older adults with chronic diseases

  A teleconsultation-based care pathway for adults 60+ with hypertension, diabetes, or dyslipidemia to see if it’s feasible and cost-saving in Malaysian primary care compared with usual clinic visits.

  Recruiting National University of Malaysia · Kuala Lumpur · NCT07843238

• Isometric Handgrip Exercise to Lower Blood Pressure in Pregnant Women

  This study tests whether doing isometric handgrip exercises can help lower blood pressure in pregnant women, including those with chronic hypertension.

  Recruiting University of Poitiers · Poitiers · NCT07607795

• Investigating microcirculation with non-invasive devices in adults with or at risk for CKD

  This study tests two non-invasive devices (HEMI and SPG-NINOX) to see how small blood vessels behave in adults with or at risk for chronic kidney disease, hypertension, or type 2 diabetes.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT07604922

• Mobile home BP monitoring with coaching after high blood pressure from pregnancy

  This program tests whether a home blood pressure monitoring system plus virtual coaching can help midlife women, 10–20 years after a hypertensive pregnancy, manage high blood pressure better than usual care.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT07599579

• Low energy availability and high blood pressure in Division I HBCU athletes

  This project will test whether not eating enough for heavy training (low energy availability) is linked to higher blood pressure and stiffer arteries in Division I HBCU athletes ages 18–25.

  Recruiting North Carolina Agriculture & Technical State University · Greensboro, North Carolina · NCT07583940

• QCZ484 extension for hypertensive patients after parent study

  This open-label extension tests long-term safety and effectiveness of QCZ484 given by injection every 6 months in people with hypertension who finished the parent study.

  Recruiting at 25 sites Phase 2 Novartis · Garden Grove, California and 24 other locations · NCT07543120

• Comparing a wearable optical blood pressure band with a traditional upper‑arm cuff for people with high blood pressure

  This study will test whether using the Aktiia G1 wearable blood pressure monitor helps people with high blood pressure control their blood pressure better than a traditional upper‑arm cuff.

  Recruiting Aktiia SA · Boston, Massachusetts · NCT07523269

• Homocysteine levels and early heart relaxation changes in newly diagnosed high blood pressure

  See if higher blood homocysteine is linked to early diastolic (heart relaxation) problems in adults recently diagnosed with high blood pressure.

  Recruiting Necmettin Erbakan University · Konya, Meram · NCT07480265

• Community health worker coaching to lower heart risk after a hypertensive pregnancy

  This program tests whether adding community health worker–led lifestyle coaching to remote blood pressure monitoring helps women who had high blood pressure during pregnancy better control blood pressure and lower heart disease risk.

  Recruiting University of South Carolina · Columbia, South Carolina · NCT07457970

• Brief bouts of exercise to lower blood pressure

  This trial will test whether short (5–10 minute) resistance or isometric exercises can lower blood pressure in adults with high or borderline high blood pressure.

  Recruiting University of Hartford · West Hartford, Connecticut · NCT07453550

• Beetroot extract effects on blood pressure and muscle oxygen during exercise in older women with high blood pressure

  This trial will test whether a beetroot supplement taken before exercise lowers blood pressure and improves muscle oxygen levels in women aged 60 to 70 with high blood pressure.

  Recruiting São Paulo State University · Bauru, São Paulo · NCT07444138

• Community health worker-led integrated care for hypertension and diabetes in Namobuddha

  This project tests if trained community health workers can improve blood pressure and blood sugar care for adults with hypertension and diabetes in Namobuddha Municipality, Nepal.

  Recruiting Kathmandu University School of Medical Sciences · Kavre, Bagmati · NCT07432126

• Monitoring progression of chronic cardiovascular conditions

  This project will collect wearable physiologic data from adults with cardiovascular conditions to see how their heart disease changes over time.

  Recruiting Prolaio · Chicago, Illinois · NCT07420907

• Electrical stimulation plus isometric exercise to improve blood flow in resistant high blood pressure

  This will try whether adding upper‑thoracic electrical stimulation (TENS) and isometric exercise to usual blood pressure medications can lower blood pressure and improve peripheral blood flow in men and women aged 50–60 with resistant hypertension.

  Recruiting Cairo University · Port Said, Port Said Governorate · NCT07383220

• Boosting the blood pressure benefit of CPAP for people with obstructive sleep apnea

  This project will test whether CPAP lowers blood pressure more in some adults with obstructive sleep apnea and whether adding a short sleep medication for people who wake up at night improves that blood pressure effect.

  Recruiting Beijing Anzhen Hospital · Beijing, Beijing Municipality · NCT07357272

• Hypertension Care Expansion in Nigeria 2.0

  This program tests a modified WHO HEARTS hypertension treatment bundle in adults with high blood pressure across five new Nigerian states to see if blood pressure can be better controlled.

  Recruiting at 49 sites Washington University School of Medicine · Mbalano, Abia State and 48 other locations · NCT07351162

• Food is Medicine Intervention to Promote Healthy Eating and Blood Pressure Control

  A 24-week program tests whether a food-as-medicine approach (FIM+DASH) helps adults with hypertension and obesity lower blood pressure and improve eating patterns compared with usual care.

  Recruiting Phase 2 University of Illinois Chicago · Chicago, Illinois and 3 other locations · NCT07332741

• Intensive hypertension management program at Cleveland Clinic

  This program will try team-based medication adjustments guided by home blood pressure readings to lower very high blood pressure in adults (18–85) with hypertension and readings over 150/95.

  Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT07232017

• Comparing short sprint cycling vs moderate continuous cycling to lower blood pressure in people with hypertension

  This trial tests whether brief, intense sprint cycling or longer moderate cycling better lowers 24-hour blood pressure in adults aged 30–59 with hypertension.

  Recruiting Unidad Enfermedades Cardiometabolicas- Hospital Interzonal General Agudos San Martin de La Plata · La Plata, Buenos Aires · NCT07229196

• Home-based isometric wall-squat exercise plus lifestyle advice for managing high blood pressure

  This project will try a 12-week home wall-squat isometric exercise program combined with lifestyle advice to see if it helps lower blood pressure in people with hypertension.

  Recruiting Northumbria University · Newcastle upon Tyne · NCT07213479

• Real-world registry of renal denervation for adults with high blood pressure in France

  This registry will collect information from adults in France who have had renal denervation to see if it controls high blood pressure and to track safety.

  Recruiting University Hospital, Grenoble · La Tronche, France · NCT07206030

• Alternate nostril breathing plus aerobic interval exercise for high blood pressure

  This will test whether adding alternate nostril breathing to aerobic interval training lowers blood pressure and heart workload in adults aged 25–50 with hypertension.

  Recruiting Foundation University Islamabad · Rawalpindi · NCT07177989

• Improving health for Black COVID-19 survivors and their caregivers

  This study is testing a telehealth program to help Black COVID-19 survivors and their caregivers improve their health and manage chronic conditions better.

  Recruiting University of South Carolina · Columbia, South Carolina · NCT05370014

Related topics

Quick answers

How many Hypertension (HTN) clinical trials are recruiting right now?

24, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in United States (11 trials), France (3 trials), Pakistan (1 trial), Nigeria (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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