Home-based isometric wall-squat exercise plus lifestyle advice for managing high blood pressure

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants will complete supervised isometric exercise sessions in a wall-squat position three times per week for 12 weeks, performed at home with remote online supervision by an exercise professional. Lifestyle change advice consistent with current guidelines will be provided alongside the exercise program. The study will collect blood pressure measurements and explore participants' experiences, attitudes, and barriers to participation to determine practical acceptability. Eligibility requires a diagnosis of hypertension with stable antihypertensive medication and excludes people with other cardiovascular disease, secondary hypertension, or musculoskeletal/neurological limitations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of Arterial Hypertension (AH) in accordance with NICE guidelines.
* Under pharmacological treatment for AH with antihypertensive drug, type and dose maintained for the previous four months.
* Blood Pressure with values \<180 and \<110 mmHg for office systolic and diastolic BP, respectively.
* Not currently engaged in any structured or supervised exercise training programme, including resistance, aerobic, or isometric exercise, defined as planned exercise performed ≥2 times per week at moderate or greater intensity, for at least three months prior to enrolment. Participants may engage in habitual physical activity; however, those meeting current physical activity recommendations (≥150 min·week-¹ of moderate-intensity or ≥75 min·week-¹ of vigorous-intensity activity, or an equivalent combination) will be excluded. Physical activity levels will be ascertained using the International Physical Activity Questionnaire (IPAQ).
* Written informed consent provided.

Exclusion Criteria:

* Body mass index \>35 kg/m2.
* Presence of cardiovascular disease beyond hypertension.
* Known orthopaedic, musculoskeletal, or neurological conditions that restrain isometric exercise execution.
* Presence of secondary hypertension
* Inability to follow verbal instructions or complete study protocol

Where it's running

• Northumbria University
  Newcastle upon Tyne, United Kingdom Recruiting

Study contacts

• Principal investigator: Gabriel Cucato, PhD — Northumbria University
• Study coordinator: Helen Llewellyn, MSc
• Email: helen.llewellyn@northumbria.ac.uk
• Phone: +447587033046

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.