Real-world registry of renal denervation for adults with high blood pressure in France
Official title: FRiEND Registry: Real Life Data From Hypertensive Patients Treated With Renal Denervation in Current Practice in France- French RENal Denervation Registry
Run by University Hospital, Grenoble · NCT07206030 · Data updated 2026-11-12
This registry will collect information from adults in France who have had renal denervation to see if it controls high blood pressure and to track safety.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | University Hospital, Grenoble Academic / other |
| Locations | 1 site (La Tronche, France) |
| Status | Recruiting |
| Started | June 23, 2025 |
| Main results expected | April 2028 |
| Study ends | October 2028 |
| Registry record updated | October 3, 2025 |
| Trial ID | NCT07206030 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (over 18) with hypertension treated with renal denervation in France, including patients treated in the past or those who will undergo the procedure, are eligible.
✕Probably not a fit
Patients who were not offered renal denervation, who refuse data collection, or who were treated outside France are unlikely to benefit from participating in this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Coordinated by Grenoble University Hospital, this national registry aims to compile exhaustive data on patients treated with renal denervation in France, including procedures performed since January 2010 and those performed prospectively after March 2025. The registry accepts all catheter types and includes cases from routine care, transitional reimbursement programs, industry registries, and randomized trials. Data collected will include patient demographics, procedural details, blood pressure outcomes, medications, and adverse events during follow-up to characterize effectiveness and safety in routine practice. The goal is to describe who receives the procedure in France and how it performs across different devices and care settings.
Why it matters
Potential benefit: If successful, the registry could clarify which patients benefit most from renal denervation, improve safety understanding, and inform clinical and reimbursement decisions in France.
How similar studies have gone: Randomized trials have shown that renal denervation can lower blood pressure and current guidelines include the technique, but comprehensive national real-world registries remain relatively limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult ( \> 18 years old) hypertensive patients treated with RDN in France whatever the catheter and the indication. This might include retrospective data for patient already treated with RDN in the past. Exclusion Criteria: * RDN not proposed to the patient, patient opposing the collection and use of his/her data for research purposes.
Where it's running
-
Chu Grenoble Alpes
La Tronche, France, France Recruiting
Study contacts
- Principal investigator: Olivier ORMEZZANO, Doctor of medicine — University Hospital, Grenoble
- Study coordinator: Olivier ORMEZZANO, Doctor of medicine
- Email: oormezzano@chu-grenoble.fr
- Phone: +33476768888
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.