Brief bouts of exercise to lower blood pressure

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will measure both immediate and longer-term blood pressure responses to brief exercise sessions. For acute effects, participants perform a single leg-press session with or without blood flow restriction while blood pressure is measured before and after. For the long-term intervention, participants follow a 6–8 week home program comparing clustered wall-sit and scattered wall-sit protocols. The study enrolls adults 18–55 with 24-hour average blood pressure >110/70 mmHg and systolic <160 mmHg, excluding those on antihypertensives or with major cardiometabolic conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18-55 yrs.
* 24 hour average BP \>110/70 mmHg, but \< 160 systolic blood pressure
* Able to provide informed consent

Exclusion Criteria:

* Currently taking anti-hypertensive medication smokers and alcohol drinkers Inability to undertake exercise intervention (resistance and isometric exercise)

Current medical history of any of the following:

hyperaldosteronism Diabetes mellitus (Type 1 or type 2) Heart disease Stroke or transient ischemic attack Peripheral neuropathy Aortic aneurysm and/or peripheral arterial disease If female, pregnancy or currently breast feeding Enrolled in another Clinical Trial of an Interventional Medicinal Product or Medical Device or other interventional study Medical condition that, in the opinion of the investigator, would make the participant unsuitable for the study On long term warfarin Allergies to blood pressure cuff materials or ultrasound gel

Previous medication history of any of the following:

hyperaldosteronism Heart disease Stroke or transient ischemic attack Peripheral neuropathy Aortic aneurysm and/or peripheral arterial disease thromboembolism Infection within limb within 3 months On long term warfarin Allergies to blood pressure cuff materials or ultrasound gel

Where it's running

• University of Hartford
  West Hartford, Connecticut, United States Recruiting

Study contacts

• Study coordinator: Jinghui Yang, PT, MPT, PhD
• Email: jiyang@hartford.edu
• Phone: 347-429-0843

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.