Clinical trial Recruiting at 1 site Interventional Ages 25 to 50

Alternate nostril breathing plus aerobic interval exercise for high blood pressure

Official title: Combined Effects of Alternate Nostril Breathing and Aerobic Interval Training on Blood Pressure and Heart Rate Products in Patients With Hypertension

Run by Foundation University Islamabad · NCT07177989 · Data updated 2026-11-12

This will test whether adding alternate nostril breathing to aerobic interval training lowers blood pressure and heart workload in adults aged 25–50 with hypertension.

More Hypertension (HTN) trials

Quick facts

Study typeInterventional
Ages25 Years to 50 Years
SexAll
Enrollment36 (estimated)
SponsorFoundation University Islamabad
Academic / other
Locations1 site (Rawalpindi)
StatusRecruiting
StartedJanuary 15, 2025
Main results expectedJanuary 15, 2026
Study endsFebruary 15, 2026
Registry record updatedSeptember 17, 2025
Trial IDNCT07177989 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 25–50 with stage 1 or 2 hypertension who can safely perform aerobic interval exercise and follow breathing instructions.

Probably not a fit

People who smoke, are pregnant, have active infections, musculoskeletal or neurological problems limiting exercise, or other contraindications to exercise are unlikely to benefit from or be eligible for this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study enrolls adults 25–50 with stage 1–2 hypertension and randomizes them to aerobic interval training with or without alternate nostril breathing. Participants attend supervised exercise and breathing sessions at Foundation University College of Physical Therapy in Islamabad. Primary outcomes include changes in systolic and diastolic blood pressure and rate pressure product, with secondary measures including quality of life. Baseline screening excludes smokers, pregnant women, active infections, and those with musculoskeletal or neurological limitations or contraindications to exercise.

Why it matters

Potential benefit: If successful, the combination could offer a low-cost, nonpharmacologic way to lower blood pressure and reduce cardiac workload while improving quality of life.

How similar studies have gone: Prior research shows aerobic interval training and alternate nostril breathing individually can lower blood pressure, but their combined effect has not been well studied.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 25- 50 years -males and females
* Patients diagnosed with stage 1 hypertension 130 - 139 / 80 - 89 mmHg and stage 2 hypertension, BP level ≥140/90 mmHg. according to AHA/ACC 2017 Guidelines-Individuals who are able to understand and follow the instructions for exercise

Exclusion Criteria:

* Diagnosed with any current infections
* subjects with diagnosed musculoskeletal or neurological conditions which hinder participation in physical activity program
* Active Smokers
* Those with any contraindication to exercise testing or training.
* Pregnant females

Where it's running

  • Foundation University College of Physical Therapy, Islamabad, 44000
    Rawalpindi, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.