Understanding how different anesthetics affect brain blood flow and oxygen levels during MRI

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the differences in cerebral blood flow and oxygen metabolism influenced by various types of anesthesia in patients requiring clinical MRI. Eligible participants, aged from birth to 18 years, will undergo an extended MRI procedure to gather additional data on cerebral hemodynamics. The study will ensure that all standard anesthesia safety protocols are maintained throughout the process. Informed consent will be obtained from all participants before their involvement in the study.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Individuals who are able to tolerate an MRI.
* Are patients scheduled for a clinically indicated MRI.
* Between birth and up to 18 years.

Exclusion Criteria:

* Presence of an MRI-incompatible device or implant (e.g. pacemakers, stents)
* Unable to tolerate the enclosed spaces and loud noises for the duration of time in scanner required to obtain an MRI.
* Preterm infants less than 25 weeks
* Any patient who is clinically too unstable to extend their MRI by up-to 7.5 minutes.

Where it's running

• Children's Hospital Los Angeles
  Los Angeles, California, United States Recruiting

Study contacts

• Principal investigator: Matthew Borzage, PhD — Children's Hospital Los Angeles
• Study coordinator: Hannah E Wiseman, MPH
• Email: hwiseman@chla.usc.edu
• Phone: 323-361-3963

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.