Condition
Follicular Lymphoma clinical trials and research
As of November 12, 2026, Find a Trial lists 68 Follicular Lymphoma clinical trials that are recruiting, at sites in 35 countries (most in United States (46), China (16), Italy (10)). By phase: Phase 2 (25), Phase 1 (13), Phase 1/2 (7), Phase 3 (3). The most active sponsors are The First Affiliated Hospital of Xiamen University (4), Masonic Cancer Center, University of Minnesota (3), Medical College of Wisconsin (3). There are also 9 NIH-funded research projects on Follicular Lymphoma, with $3.4 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 68Clinical trials
- 9NIH research projects
- 35Countries
Newest Follicular Lymphoma clinical trials
All recruiting trials (68)
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Non-Hodgkin Lymphoma Sample Collection for MRD Testing
This study tests a blood-based and tissue-based approach to see if a molecular residual disease test can detect lingering cancer in adults with aggressive NHL who are starting standard therapy.
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MK-1045 and Rituximab in Follicular Lymphoma
This study tests whether adding MK-1045 to rituximab can help people with follicular lymphoma after standard therapy.
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Mosunetuzumab and Zeprumetostat in Follicular Lymphoma
This study tests whether a combination of Mosunetuzumab and Zeprumetostat can help adults with follicular lymphoma.
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Zanubrutinib plus obinutuzumab and lenalidomide for first-line follicular lymphoma
This trial tests whether the combination of zanubrutinib, obinutuzumab, and lenalidomide is safe and effective as a chemotherapy-free first treatment for adults with untreated follicular lymphoma.
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LY4584180 with rituximab for adults with previously treated B‑cell lymphomas
This trial will test LY4584180 together with rituximab in adults with previously treated B‑cell lymphomas to see if it is safe, reaches useful levels in the blood, and can help control the disease.
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Rituximab and Tafasitamab with Allogeneic NK Cells for relapsed or refractory B-cell NHL
This trial tests whether giving allogeneic NK cells with Rituximab, Tafasitamab, and IL-2 can help people with relapsed or refractory B-cell non-Hodgkin lymphoma who have tried at least two prior therapies.
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Mosunetuzumab by subcutaneous injection as first-line therapy for low tumor burden follicular lymphoma
This trial tests whether subcutaneous mosunetuzumab can be safely and effectively used as initial treatment for adults with newly diagnosed follicular lymphoma with low tumor burden.
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Odronextamab for previously untreated low-tumor-volume advanced follicular lymphoma
This study will try odronextamab, an antibody immunotherapy, in adults with previously untreated low-tumor-volume advanced follicular lymphoma to see if it is safe and effective.
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Fixed-duration zanubrutinib plus bendamustine and obinutuzumab for newly diagnosed advanced follicular lymphoma
This tests a six-cycle combination of zanubrutinib, bendamustine, and obinutuzumab for adults with newly diagnosed advanced-stage follicular lymphoma.
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Reduced-dose radiation therapy for people with follicular or marginal zone lymphoma
This trial will test whether very low-dose radiation controls stage I–II follicular or marginal zone lymphoma as well as standard-dose radiation while causing fewer side effects.
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Skin tests to check biotherapy allergies in cancer patients
We are testing skin tests to see if cancer patients treated with biotherapies have allergies or hypersensitivity to those drugs.
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Golcadomide plus rituximab versus investigator's choice for relapsed or refractory follicular lymphoma
This trial tests whether combining golcadomide with rituximab works better than standard investigator‑selected treatments for adults with relapsed or refractory follicular lymphoma who have had at least one prior systemic therapy.
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Personalized exercise and nutrition program to reduce cancer-related fatigue
This program will try a personalized exercise and diet plan to reduce fatigue for adults with indolent lymphomas (including CLL/SLL and follicular lymphoma).
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ImmunoPET imaging for detecting malignant cancers
This study is testing a new imaging method to see if it can better detect certain types of cancer in patients who have or might have these diseases.
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Assessing Epcoritamab for Adult Patients with Advanced Lymphoma
This study is testing if a new skin injection called epcoritamab can help adults with advanced lymphoma feel better and improve their health.
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Treatment for patients with relapsed follicular lymphoma using Axicabtagene Ciloleucel Injection
This study is testing a new treatment called Axicabtagene Ciloleucel Injection to see if it can help Chinese patients with relapsed follicular lymphoma who have already tried other therapies.
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Long-term safety of lisocabtagene maraleucel in patients with relapsed follicular lymphoma
This study is testing the long-term safety of a treatment called lisocabtagene maraleucel in people with relapsed follicular lymphoma who have already received it.
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Tafasitamab with lenalidomide and rituximab for newly diagnosed follicular and marginal zone lymphoma
This trial will test whether adding tafasitamab to rituximab and lenalidomide is safe and helps people newly diagnosed with follicular lymphoma or marginal zone lymphoma.
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Evaluating vaccine responses in patients with multiple myeloma and non-Hodgkin lymphoma after CAR-T treatment
This study tests how well vaccines work in people with multiple myeloma and non-Hodgkin lymphoma after they have received CAR-T treatment.
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Radiation and Tiselizumab with RCHOP for Bulky Follicular Lymphoma
This study is testing if adding radiation to a combination of Tiselizumab and R-CHOP chemotherapy can help people with bulky follicular lymphoma feel better and improve their treatment results.
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Combination treatment for relapsed or refractory follicular lymphoma
This study is testing a new combination of three medications to see if it can help people with relapsed or refractory follicular lymphoma feel better.
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Combining Zanubrutinib and Obinutuzumab for Treating Newly Diagnosed Follicular Lymphoma
This study is testing a new combination of two medications, Zanubrutinib and Obinutuzumab, to see if they can help people with newly diagnosed follicular lymphoma feel better and stay healthy.
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Preventing CAR-T cell toxicities with emapalumab
This study is testing if a drug called emapalumab can help prevent side effects in people with large B-cell non-Hodgkin's lymphoma who are receiving another treatment called axicabtagene ciloleucel.
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Treatment for relapsed or refractory B-cell lymphoma using SynKIR-310
This study is testing a new treatment called SynKIR-310 to see if it can help adults with relapsed or refractory B-cell lymphoma feel better.
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Gene therapy for certain blood cancers
This study is testing a new gene therapy called VNX-101 to see if it can help people with certain types of blood cancers that haven't responded to other treatments.
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Epcoritamab treatment for patients with follicular lymphoma not responding to initial therapy
This study is testing if a new treatment called epcoritamab can help people with follicular lymphoma who didn't respond well to their first therapy.
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Combining rituximab and zanubrutinib for treating indolent B-cell lymphomas
This study is testing if combining two medications, rituximab and zanubrutinib, can help people with untreated indolent B-cell lymphomas feel better and improve their treatment outcomes.
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Using CAR T cells to treat certain types of B cell lymphomas
This study is testing a new CAR T cell therapy to see if it can help adults with certain types of B cell lymphomas that haven't improved with other treatments.
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Observational study on CAR-T therapy for lymphoma in Italy
This study looks at how well CAR-T therapy works and its side effects for people with lymphoma in Italy by tracking their health over three years.
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Combining Chidamide and Linperlisib for treating difficult cases of follicular lymphoma
This study is testing if combining two drugs, Chidamide and Linperlisib, can help people with tough cases of follicular lymphoma who haven't responded to other treatments.
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Combining lenalidomide with G-CHOP for treating newly diagnosed DLBCL with FL
This study is testing if adding lenalidomide to the G-CHOP treatment can help people newly diagnosed with diffuse large B-cell lymphoma and follicular lymphoma feel better and live longer.
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Study of crushed venetoclax tablets dissolved in liquid for pediatric patients
This study tests if crushing venetoclax tablets and mixing them with liquid helps children with blood cancers absorb the medication better and stay safe while taking it.
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Treatment for high tumor burden follicular lymphoma using obinutuzumab and CC-99282
This study is testing if a new combination of obinutuzumab and CC-99282 can help people with high tumor burden follicular lymphoma who haven't been treated before feel better and live longer.
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Combining CAR T-cell therapy with radiation for relapsed follicular lymphoma
This study is testing if combining a new CAR T-cell therapy with radiation can help people with relapsed follicular lymphoma feel better and have fewer side effects.
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Using CD79b-19 CAR T cells to treat Non-Hodgkin Lymphoma
This study is testing a new treatment using modified immune cells to see if it can help people with relapsed or hard-to-treat Non-Hodgkin Lymphoma.
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Testing ONM-501 alone and with Cemiplimab for advanced solid tumors and lymphomas
This study is testing a new treatment called ONM-501, both alone and with another drug called cemiplimab, to see if it can help people with advanced solid tumors and lymphomas who have run out of other treatment options.
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Using LV20.19 CAR T-Cells with Pirtobrutinib for B-cell Malignancies
This study is testing a new treatment combining LV20.19 CAR T-cells with pirtobrutinib to see if it helps adults with tough-to-treat B-cell cancers feel better.
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Comparing radiotherapy alone versus with Obinutuzumab for early stage follicular lymphoma
This study is testing if adding Obinutuzumab to radiation therapy helps people with early-stage follicular lymphoma do better than just radiation alone.
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Observing the effects of obinutuzumab for untreated follicular lymphoma
This study looks at how well the drug obinutuzumab works and how safe it is for people with untreated follicular lymphoma in real-life settings.
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Combining obinutuzumab and lenalidomide for treating relapsed follicular lymphoma
This study is testing if combining obinutuzumab and lenalidomide can help people in China with relapsed follicular lymphoma feel better and live longer, while keeping their current treatment plans.
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Evaluating biomarkers in advanced follicular lymphoma treatment
This study is trying to see if certain genetic changes in patients with advanced follicular lymphoma can help doctors choose the best chemotherapy treatment after they've received immunotherapy.
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Stem cell transplant using a specific preparative regimen for blood cancers
This study is testing a new way to prepare for a stem cell transplant using a special combination of medications and radiation to see if it helps people with acute leukemia who are in remission.
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Epcoritamab plus rituximab as first treatment for follicular lymphoma
This trial tests whether adding epcoritamab to rituximab is safe and effective as the first treatment for adults with untreated follicular lymphoma.
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Evaluating CTX112 for B-cell malignancies
This study is testing a new type of CAR T cell therapy called CTX112 to see if it can safely help people with tough-to-treat B-cell cancers.
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Oral AS-1763 treatment for patients with certain blood cancers
This study is testing a new oral medication called AS-1763 to see if it can help patients with certain blood cancers who haven't had success with other treatments.
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Evaluating SGR-1505 for treating mature B-cell neoplasms
This study is testing a new oral medication called SGR-1505 to see if it is safe and effective for people with certain types of B-cell lymphomas that have not responded to other treatments.
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Evaluating the effectiveness and safety of tisagenlecleucel therapy in Brazilian patients with B-cell malignancies
This study is testing how well and safely a treatment called tisagenlecleucel works for Brazilian patients with certain types of blood cancers, including lymphoma and leukemia, over a long follow-up period.
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Treatment with Mosunetuzumab for newly diagnosed Follicular Lymphoma
This study is testing if a new treatment called mosunetuzumab can help people who have just been diagnosed with follicular lymphoma feel better before they start other treatments.
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IKS03 treatment for advanced B cell non-Hodgkin lymphomas
This study is testing a new treatment called IKS03 for people with advanced B cell non-Hodgkin lymphoma to see how safe and effective it is.
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Evaluating zanubrutinib treatment in patients with certain blood cancers
This study is trying to see how well zanubrutinib works and how it affects the lives of adults with certain blood cancers like Waldenström's Macroglobulinemia and Chronic Lymphocytic Leukemia.
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Treatment for B-cell malignancies using BGB-16673
This study is testing a new drug called BGB-16673 to see if it can safely help people with different types of B-cell cancers.
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Local production of CAR T-cells for treating B-Cell cancers
This study is testing whether making CAR T-cells locally can help patients with B-Cell lymphoma and leukemia have a safe and effective treatment.
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Assessing ctDNA for monitoring lymphoma patients receiving CAR therapy
This study is testing if measuring tumor DNA in the blood can help doctors keep track of lymphoma patients receiving CAR therapy and see if their cancer is coming back sooner than traditional scans.
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Exploring BGB-16673 for treating B-cell malignancies
This study is testing a new drug called BGB-16673 to see if it can safely help people with certain types of B-cell cancers, like Marginal Zone Lymphoma and Follicular Lymphoma, who haven't had success with other treatments.
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Combining Loncastuximab Tesirine and Rituximab for treating relapsed Follicular Lymphoma
This study is testing if combining two treatments, Loncastuximab Tesirine and Rituximab, can help people with relapsed Follicular Lymphoma feel better compared to current options.
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Orelabrutinib plus rituximab followed by orelabrutinib maintenance for relapsed or refractory follicular lymphoma
This trial tests whether combining orelabrutinib with rituximab, followed by orelabrutinib alone, helps people whose follicular lymphoma has come back or stopped responding.
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First-line treatment for follicular and marginal zone lymphoma using mosunetuzumab and lenalidomide
This study is testing if a new combination of treatments can help adults with untreated follicular or marginal zone lymphoma feel better and improve their response to therapy.
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Oral treatment with LP-168 for patients with certain blood cancers
This study is testing an oral treatment called LP-168 to see if it can help adults with certain types of blood cancers that have come back or didn't respond to other treatments.
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Using modified T cells to treat relapsed or refractory Non-Hodgkin Lymphoma
This study is testing a new treatment using modified T cells to see if it can help people with relapsed or hard-to-treat Non-Hodgkin Lymphoma.
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Using stem cell transplant and Polatuzumab Vedotin for treating B-cell lymphomas
This study is testing if a stem cell transplant followed by a new drug called Polatuzumab Vedotin can help people with different types of B-cell lymphomas feel better.
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Treatment using modified T cells for certain types of lymphoma
This study is testing a new treatment using modified immune cells to see if it can help people with certain types of lymphoma that haven't responded to other therapies.
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CAR-T cell therapy for patients with relapsed B cell cancers
This study is testing a new CAR-T cell therapy for adults with relapsed B cell cancers to see how well it works and if different manufacturing methods make a difference in treatment outcomes.
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Treatment for relapsed or refractory CD19+ lymphoid diseases using engineered T cells
This study is testing a new treatment using specially modified immune cells to help adults and children with certain types of blood cancers that haven't responded to other therapies.
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Evaluating immune responses to influenza vaccination in lymphoma patients
This study is testing how well the flu vaccine works for people with lymphoma by checking their immune responses after getting vaccinated.
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AI-based precision oncology clinical trial matching and registry
This study is testing whether an AI tool can help match cancer patients with the right clinical trials based on their specific cancer details to see if it improves their chances of getting into trials and their overall outcomes.
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Long-term follow-up of patients receiving CAR-T cell therapy
This study is tracking patients who have received CAR-T cell therapy for up to 15 years to see how well the treatment works over time and if there are any long-term health issues.
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Hematopoietic stem cell transplant for blood cancers
This study is testing two different ways of doing stem cell transplants for people with blood cancers to see which method works better and is safer.
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Understanding the progression of follicular lymphoma
This study is trying to learn more about how follicular lymphoma develops in adults who haven't started treatment yet, by collecting samples and information to help find better treatments in the future.
NIH-funded research (9)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Preventing follicular lymphoma progression with precision therapy
This grant tests a targeted approach to stop follicular lymphoma from getting worse or turning into a more aggressive cancer.
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Follicular Lymphoma: Better Diagnosis and Personalized Risk in B-Cell Lymphomas
This NIH grant aims to improve how doctors diagnose and predict outcomes for people with follicular lymphoma by finding reliable biomarkers to guide treatment decisions.
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IRF4's role in shaping the tumor environment in follicular lymphoma
This grant aims to understand how a molecule called IRF4 changes the tumor surroundings in follicular lymphoma to identify potential new ways to help patients.
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Gene test to predict early treatment failure in follicular lymphoma
A lab test that reads genes in lymphoma biopsy tissue to spot people with follicular lymphoma who are likely to have their disease return within two years after standard immunochemotherapy.
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How mutant STAT6 affects follicular lymphoma
This project looks at how a gene change called STAT6 affects follicular lymphoma to help find better treatments for people with this cancer.
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Preventing the progression of follicular lymphoma with targeted therapy
This study is looking at how slow-growing follicular lymphomas can change into more aggressive forms, and it's working to find personalized treatments that target the specific factors that help these tumors survive, so we can help patients live better and longer.
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Developing a test to predict early treatment failure in follicular lymphoma
This study is looking to help doctors better predict which patients with follicular lymphoma might not respond well to standard treatment, using a special test on tissue samples to find important genetic clues, so they can create more personalized treatment plans for you.
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Understanding how mutant STAT6 affects follicular lymphoma
This study is looking at how certain changes in a gene called STAT6 affect follicular lymphoma, a type of cancer, to help find better treatments that work for patients based on their unique genetic makeup.
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Understanding how IRF4 affects the tumor environment in follicular lymphoma
This study is looking at how a protein called IRF4 affects the environment around tumors in people with follicular lymphoma, a type of blood cancer, to find new ways to improve treatment and help patients feel better.
Related topics
Quick answers
How many Follicular Lymphoma clinical trials are recruiting right now?
68, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 35 countries. The most sites are in United States (46 trials), China (16 trials), Italy (10 trials), Australia (7 trials), Spain (7 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 25, Phase 1: 13, Phase 1/2: 7, Phase 3: 3. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.