ImmunoPET imaging for detecting malignant cancers
Official title: CD70-targeted PET/ CT in the Diagnosis of Malignant Cancers
Run by RenJi Hospital · NCT06852638 · Data updated 2026-11-12
This study is testing a new imaging method to see if it can better detect certain types of cancer in patients who have or might have these diseases.
Quick facts
| Phase | Phase 2 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | RenJi Hospital Academic / other |
| Locations | 1 site (Shanghai) |
| Status | Recruiting |
| Started | December 23, 2024 |
| Main results expected | December 23, 2026 |
| Study ends | December 23, 2026 |
| Registry record updated | May 12, 2026 |
| Trial ID | NCT06852638 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18-80 with confirmed or suspected renal cancer, lymphoma, or nasopharyngeal carcinoma.
✕Probably not a fit
Patients who are pregnant or have severe hepatic and renal insufficiency may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on optimizing a new imaging technique called CD70-targeted immuno-positron emission tomography/computed tomography (immunoPET/CT) to evaluate its effectiveness in diagnosing malignant cancers such as renal cancer, lymphoma, and nasopharyngeal carcinoma. Patients with confirmed or suspected malignancies will undergo whole-body scans after receiving a tracer injection, and the imaging results will be quantitatively analyzed. The study aims to compare the diagnostic efficacy of this new imaging method against conventional imaging techniques.
Why it matters
Potential benefit: If successful, this approach could significantly improve the accuracy of cancer diagnosis and treatment monitoring for patients.
How similar studies have gone: While this approach is innovative, similar imaging techniques have shown promise in other studies, indicating potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 18-80 year-old and of either sex; * Histologically confirmed diagnosis of renal cancer (especially ccRCC)/lymphoma/NPC or suspected renal cancer/lymphoma/NPC by diagnostic imaging; * Capable of giving signed informed consent, including compliance with the requirements and restrictions in the informed consent form (ICF) and this protocol. Exclusion Criteria: * Pregnancy; * Severe hepatic and renal insufficiency; * Allergic to single-domain antibody radiopharmaceuticals.
Where it's running
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Renji Hospital, School of Medicine, Shanghai Jiao Tong University
Shanghai, China Recruiting
Study contacts
- Principal investigator: Weijun Wei, Ph.D. & M.D. — Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University
- Study coordinator: Weijun Wei, Ph.D. & M.D.
- Email: wwei@shsmu.edu.cn
- Phone: 15000083153
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.