Clinical trial Recruiting at 1 site Phase 2 Interventional Ages 18 to 80

ImmunoPET imaging for detecting malignant cancers

Official title: CD70-targeted PET/ CT in the Diagnosis of Malignant Cancers

Run by RenJi Hospital · NCT06852638 · Data updated 2026-11-12

This study is testing a new imaging method to see if it can better detect certain types of cancer in patients who have or might have these diseases.

Quick facts

PhasePhase 2
Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment300 (estimated)
SponsorRenJi Hospital
Academic / other
Locations1 site (Shanghai)
StatusRecruiting
StartedDecember 23, 2024
Main results expectedDecember 23, 2026
Study endsDecember 23, 2026
Registry record updatedMay 12, 2026
Trial IDNCT06852638 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18-80 with confirmed or suspected renal cancer, lymphoma, or nasopharyngeal carcinoma.

Probably not a fit

Patients who are pregnant or have severe hepatic and renal insufficiency may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on optimizing a new imaging technique called CD70-targeted immuno-positron emission tomography/computed tomography (immunoPET/CT) to evaluate its effectiveness in diagnosing malignant cancers such as renal cancer, lymphoma, and nasopharyngeal carcinoma. Patients with confirmed or suspected malignancies will undergo whole-body scans after receiving a tracer injection, and the imaging results will be quantitatively analyzed. The study aims to compare the diagnostic efficacy of this new imaging method against conventional imaging techniques.

Why it matters

Potential benefit: If successful, this approach could significantly improve the accuracy of cancer diagnosis and treatment monitoring for patients.

How similar studies have gone: While this approach is innovative, similar imaging techniques have shown promise in other studies, indicating potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged 18-80 year-old and of either sex;
* Histologically confirmed diagnosis of renal cancer (especially ccRCC)/lymphoma/NPC or suspected renal cancer/lymphoma/NPC by diagnostic imaging;
* Capable of giving signed informed consent, including compliance with the requirements and restrictions in the informed consent form (ICF) and this protocol.

Exclusion Criteria:

* Pregnancy;
* Severe hepatic and renal insufficiency;
* Allergic to single-domain antibody radiopharmaceuticals.

Where it's running

  • Renji Hospital, School of Medicine, Shanghai Jiao Tong University
    Shanghai, China
    Recruiting

Study contacts

  • Principal investigator: Weijun Wei, Ph.D. & M.D. — Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University
  • Study coordinator: Weijun Wei, Ph.D. & M.D.
  • Email: wwei@shsmu.edu.cn
  • Phone: 15000083153

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.